Rapid prototyping (RP) uses a cycle where a real model is made by explicitly adding material as thin cross-sectional layers. Fused deposition modelling (FDM) 3D printer is being use for synthesis of ABS based bone hammer. Response surface methodology (RSM) based L27 design of experiment were adopted to perform the experiment using four influencing parameters such as layer thickness, infill percentage, orientation and nozzle temperature for the three responses deflection, hardness and weight. Response surface methodology was used for modelling and optimization of considered process parameters. In present investigation, it is evident that bone hammer fabrication process parameters have been optimized on data such as bone hammer weight 19.8091g, hardness 104.5921 BHN, and force of 15 degree deflection 36.0681 N has been produced with RSM prediction with influence of process parameters such as layer thickness 0.250 mm, infill percentage 63.3333, orientation 60 degree, nozzle temperature 240°C.
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