AimThe present study was designed to investigate the association of ABO blood group types in cervical cancer.
Material and MethodsThe study sample consisted of 248 subjects as confirmed cases of cervical cancer and 254 individuals as controls. Data about the blood group types was collected from the blood bank of Govt. Medical College, Jammu.
ResultsA statistical significant difference in the distribution of ABO blood groups between the patients and controls was observed. The incidence of B-type group was the highest in the patients as well as in the control subjects this was followed by O blood group.
ConclusionThe results concluded that B blood group may be considered as a risk factor in carcinoma of the cervix.
Background:Anemias are the blood disorders characterized by reduction in the number of circulating red blood cells, the amount of hemoglobin, or the volume of packed red cells in blood. Chromosomal aberrations have often been reported from the bone marrow as well as cultured lymphocytes of the anemic patients.Aims:The aims of the study were to find out the commonest type of anemia occurring in the population of Jammu, India and to find out the chromosomal changes involved in the disorder.Material and Methods:Present study has been carried out on the bone marrow samples from 53 clinically diagnosed anemic patients. Cytogenetic study was carried out on slides prepared from these samples. Noncytogenetic factors like age, sex, religion, blood groups, family history of anemia, socioeconomic status, etc. have also been included in the study.Results:Megaloblastic anemia was found to be the commonest type of anemia. Centromere stretching, chromatid breaks, gaps, and elongation of chromosomes were recorded in patients with megaloblastic anemia and combined deficiency anemia. However, structural changes and numerical changes were totally absent.Conclusion:The commonest anemia among the people of Jammu region is megaloblastic anemia and its prevalence is increasing every year. Also, megaloblastic anemia is always associated with reversible cytogenetic changes.
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