Background: Urinary tract infection (UTI) is a condition where the urinary tract is infected by pathogens, causing microorganisms in urine. The gold standard examination for UTI is urine culture. Urine culture has some weaknessess. It takes around two days to get result and requires quite expensive cost. Leukocyte esterase and nitrite are relatively inexpensive, less-time consuming and easy to do laboratory tests that can detect UTI. Aim: To explore the correlation of leukocyte esterase and nitrite with urine culture in UTI patients. Methods: A cross sectional study of 42 UTI adult patients which treated at Dr. Kariadi hospital Semarang in September until October Gambar 3 Grafik hubungan antara leukosit esterase urin dan kultur urin