Uji korelasi leukosit esterase dan nitrit dengan kultur urin pada infeksi saluran kemih

Malau, Ursula Nauli; Adipireno, Purwanto

doi:10.15562/ism.v10i1.343

Cited by 4 publications

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“…Meanwhile there was 1 result or 2.5% positive leukocyte esterase and negative urine culture, 7 results or 16.7% negative leukocyte esterase and positive urine culture. Apart from that, previous research conducted by Malau & Adipireno (2019) concluded that there was a weak positive relationship between leukocyte esterase results and urine culture results. Some of the reasons why leukocyte esterase results are positive while urine culture results are negative are the presence of leukocytes in the urine (pyuria) indicating an inflammatory process that can occur in the urine secretion system, starting from the kidneys to the urethra, but this inflammation is notIt is always caused by the presence of bacteria so this could be one of the factors causing the difference in results between leukocyte esterase results and urine culture.…”

Section: Resultsmentioning

confidence: 88%

“…The difference in results between nitrite and urine culture in detecting the presence of bacteria is caused by several factors, including that the nitrite test has a sensitivity of 35 -85% in detecting UTI-causing bacteria which are unable to convert nitrate to nitrite. Meanwhile, previous research by Malau & Adipireno (2019) concluded that there was no significant relationship between nitrite results and urine culture results. Some of the causes of differences in results between nitrite and urine culture depend on how long the nitrate reducing bacteria infects the bladder, apart from that it takes a minimum of 4 hours for the bacteria to be in the bladder so they can convert nitrate into nitrite.…”

Section: Resultsmentioning

confidence: 95%

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Relationship between urinary track infection screening tests and urine culture results in patients with suspect urinary track infection

Indriati,

Silviani

2024

JoIMedLabS

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Background: Urinary tract infection (UTI) is a common disease found in the world. Gold standard for the diagnosis of UTI is urine culture, but this examination has the disadvantage of taking longer results. As a screening test, urine dipstick and urine flowcytometry provide more rapid diagnosis of UTI. Objectives: The purpose of this study was to determine the relationship between the results of the dipstick test and UF4000 with urine culture. Materials and Methods: This study used an analytic observational method with a cross sectional approach, with accidental sampling. The samples obtained was 38 samples from patients at the Clinical Laboratory of Prodia Diponegoro and Prodia SDP. Results: The results showed that there was 84.2% concordance between leukocyte esterase results and culture results, and 31.6% concordance between nitrite results and culture results, 97.4 5% concordance between urine flowcytometry results and urine culture results. Conclusions: Based on the Chi square statistical, it was concluded that there were relationship between Urine culture and leukocyte esterase (p-value 0.000), nitrite (p-value 0.004, urine flowcytometri (p-value 0.000). Both of these screening tests can be used to help diagnose UTI, but the gold standard for UTI still uses urine culture result.

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Section: Resultsmentioning

confidence: 88%

Section: Resultsmentioning

confidence: 95%

Relationship between urinary track infection screening tests and urine culture results in patients with suspect urinary track infection

Indriati,

Silviani

2024

JoIMedLabS

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“…Leukosit esterase merupakan suatu keadaan dimana terdapatnya leukosit yang mengeluarkan enzim esterase yang disebabkan oleh adanya bakteri golongan Enterobacteriaceae. 5,6 Kultur urin merupakan pemeriksaan baku emas untuk mendiagnosis ISK, interpretasi hasil dengan menghitung jumlah kuman yang ada pada media kultur. 7 Pada anak, ISK merupakan infeksi yang paling sering terjadi setelah infeksi saluran napas.…”

Section: Pendahuluanunclassified

Perbandingan Leukosituria, Nitrit, Leukosit Esterase dengan Kultur Urin dalam Mendiagnosis Infeksi Saluran Kemih pada Anak

Sabriani¹,

Umboh²,

Manoppo³

2021

MSJ

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Urinary tract infection (UTI) in children is the most common infection after upper airway infection. The diagnosis of UTI is based on urine culture, however, this examination takes a longer time and is quite expensive. Therefore, the diagnosis of UTI can also be confirmed by using leukocyturia, nitrite, and leukocyte esterase tests although they can not replace urine culture as the gold standard. This study was aimed to determine the accuracy of positive leukocyturia, positive nitrite, positive leukocyte esterase examination, combination of positive leukocyturia and nitrite examinations, positive leukocyturia and leukocyte esterase, and leukocyturia, nitrite, positive leukocyte esterase in diagnosing UTI. This was a literature review study. The results of the literature review showed that the range of accuracy of UTI diagnosis using positive leukocyte esterase examinations was 9-6.8%, positive nitrite was 2.8-100%, leukocyte esterase was 13.7-86%, combination of positive leukocyturia and nitrite had a sensitivity value of 33 %, and specificity of 94%, combination of positive leukocytic and leukocytic esterase had a sensitivity value of 70% and a specificity of 90%, and combination of leukocyturia, nitrite, and leukocyte esterase had an accuracy range of 100%. In conclusion, these examinations coul be used to confirm the diagnosis of UTI in children especially if the urine culture can not be performed on them.Keywords: urinary tract infection (UTI), leukocyturia, nitrite, leukocyte esterase, urine culture, children Abstrak: Infeksi saluran kemih (ISK) merupakan infeksi yang paling sering terjadi pada anak setelah infeksi saluran napas atas. Diagnosis ISK ditegakkan berdasarkan hasil pemeriksaan kultur urin, namun pemeriksaan ini membutuhkan waktu yang lama dan biaya yang cukup mahal. Pemeriksaan leukosituria, nitrit, dan leukosit esterase juga membantu dalam mendiagnosis ISK, namun ketiga pemeriksaan ini belum dapat menggantikan kultur urin sebagai baku emas untuk mendiagnosis ISK. Penelitian ini bertujuan untuk mengetahui seberapa besar ketepatan pemeriksaan leukosituria positif, nitrit positif, leukosit esterase positif, gabungan pemeriksaan leukosituria dan nitrit positif, leukosituria dan leukosit esterase positif, dan gabungan leukosituria, nitrit, leukosit esterase positif dalam mendiagnosis ISK. Jenis penelitian ialah literature review. Hasil penelitian menunjukkan kisaran ketepatan diagnosis ISK menggunakan pemeriksaan leukosituria positif yaitu 9-6,8%, nitrit positif sebesar 2,8-100%, leukosit esterase sebesar 13,7-86%, gabungan leukosituria dan nitrit positif memiliki nilai sensitivitas 33%, dan spesifisitas sebesar 94%, gabungan leukosituria dan leukosit esterase positif memiliki nilai sensitivitas 70% dan spesifisitas sebesar 90%, serta gabungan pemeriksaan leukosituria, nitrit, dan leukosit esterase memiliki kisaran ketepatan sebesar 100%. Simpulan penelitian ini ialah pemeriksan-pemeriksaan tersebut dapat membantu menegakkan diagnosis ISK pada anak terutama bila kultur urin tidak memungkinkan dilakukan.Kata kunci: infeksi saluran kemih (ISK), leukosituria, nitrit, leukosit esterase, kultur urin, anak

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“…Dinyatakan ISK jika hasil kulturnya adalah kategori 3. Hasil penelitian ini tidak sejalan dengan penelitian Malau (2019) yang tidak mendapatkan hubungan antara nitrit dengan kultur urin (p-value 0,272) Beberapa kelemahan pada uji nitrit diantaranya hasil negatif palsu karena bakteri yang terdapat di urin bukan bakteri penghasil nitrit, atau proses metabolisme nitrat menjadi nitrit sangat cepat, sehingga hanya sesaat saja berada dalam urin. Makan sayuran seperti selada dan bayam dapat memberikan hasil positif palsu pada pemeriksaan nitrit dalam urin, karena sayuran tersebut mengandung nitrit, tetapi hasil kulturnya negatif Sesuai pada tabel 5 hasil uji bivariat dinyatakan tidak ada hubungan antara DM dengan kejadian ISK dengan p-value sebesar 0,279 (p-value>0,05).…”

Section: Hubungan Antara Hasil Uji Dipstik (Leukosit Esterase Nitrit Dan Glukosuria) Dengan Kejadian Iskunclassified

Hubungan Hasil Dipstik Urin (Leukosit Esterase, Nitrit dan Glukosuria) dengan Kejadian ISK pada Pegawai

Tuntun

Aminah

2021

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A urine test with a dipstick is an alternative test for rapid leukocyte and bacterial tests to support the diagnosis of urinary tract infection (UTI). The purpose of this study was to determine the relationship between the results of the dipstick test (leukocyte esterase, nitrite, and glucosuria) with the incidence of UTI. The research is observational analytic with a cross-sectional design, which was conducted in September-October 2020, at Campus "X". The population is 351 people, with 92 respondents. A urine test was performed with a dipstick and culture. The dipstick test is a screening step, while the culture is used to confirm the microbiological diagnosis of UTI. The results of the study using the dipstick test showed that 17 people (18,48%) were positive for leukocyte esterase, 27 people (29,35%) were positive for nitrite, and 7 people (7,61%) were positive for glucosuria (DM). The results of the urine culture test showed that 20 people (21,74%) had UTI, which consisted of 11 women and 9 men. There is a relationship between leukocyte esterase and nitrite on UTI (p-value 0.00), but there is no relationship between glucosuria and UTI (p-value 0,279). The use of the dipstick test as a screening test for the incidence of UTI has been used, but it is still necessary to continue with a culture test to be able to make a diagnosis of UTI.

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Uji korelasi leukosit esterase dan nitrit dengan kultur urin pada infeksi saluran kemih

Cited by 4 publications

References 0 publications

Relationship between urinary track infection screening tests and urine culture results in patients with suspect urinary track infection

Relationship between urinary track infection screening tests and urine culture results in patients with suspect urinary track infection

Perbandingan Leukosituria, Nitrit, Leukosit Esterase dengan Kultur Urin dalam Mendiagnosis Infeksi Saluran Kemih pada Anak

Hubungan Hasil Dipstik Urin (Leukosit Esterase, Nitrit dan Glukosuria) dengan Kejadian ISK pada Pegawai

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