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The paper examines changes in carbonyl iron and nickel powders subjected to model biological media: water media and media containing human blood plasma. It is established that carbonyl iron powder interacts with biomedia containing blood plasma six times as fast as with water media. No oxidation or corrosion is observed in the process. The magnetic properties of the powder after the interaction with plasma-containing media do not practically deteriorate. Iron powder is intensively absorbed by blood plasma, Fe 3+ ions forming complex compounds with proteins. On the contrary, carbonyl nickel is not absorbed by blood plasma for five days, and the powder specific surface area and particle morphology remain practically unchanged after the interaction. Blood plasma seems to dissolve and transform metals according to the human body's demands. In the case of carbonyl iron, this process proceeds faster than corrosion does. In the case of carbonyl nickel, the opposite is observed.Keywords: carbonyl iron, carbonyl nickel, biological media, human blood plasma, powder specific surface area, magnetic properties.Superfine metal powders are widely used in many areas including medicine; therefore, unwanted side effects may occur in their production and application. A clear idea of how superfine metal powers affect the human body is crucial for their implementation and use. To grasp this idea, the transformation of powders in the body's biological media should be studied.The objective of this paper is to study how model biological media affect the physical, chemical, and magnetic properties of iron and nickel powders. The results may further be used as reference for other superfine iron-or nickel-based powders.

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