No abstract

Recently, a number of children with chronic inflammatory diseases of the digestive organs is growing in Russia. This article considers the clinical manifestations of children with chronic gastro-duodenal diseases. The problems of the chronic diseases of gastrointestinal tract are relevant due to the significant prevalence the digestive diseases in children, among them the leading place is a gastro-duodenal pathology. The high prevalence of this pathology in children is an important social and medical problem. An analysis of the prevalence of digestive diseases among the children in the Russian Federation indicates that over the last 20 years there is a significant increase in gastrointestinal pathology in children and uncontrolled increase in the incidence of diseases of the stomach and duodenum. The clinical manifestations of a chronic gastro-duodenal pathology are various and depend on the degree of structural changes of the organs, their location, a stage of the pathological process, functional status and disturbance of metabolic processes in the body. Chronic diseases of the digestive system in children often begin in pre-school and school age. The gastro-duodenal diseases have a relapsing course, they are a cause of anatomical changes of the body. In the future, it leads to loss of earning capacity and disability among the adult population.

Recently, in Russia the number of children with chronic inflammatory diseases of the digestive system grows steadily. Chronic diseases of the digestive system in children often begin in pre-school and school age. This article discusses the objective criteria of the chronic diseases of the digestive system in children. This pathology is an important social and medical problem among children. Today, there are many children with digestive pathology. The leading is gastro-duodenal pathology. Analysis of the above data shows the high complexity of the diagnostic evaluation of different symptoms that can only be detected on palpation of the anterior abdominal wall in children with combined pathology of the organs of the gastro-duodenal zone. This is due to the co-morbidity of development of pathological process. On the other part, however, the authors observed a logical relation in the frequency of occurrence of these or other symptoms depending on the extent and nature of the lesion of the stomach, duodenum, biliary system, pancreas in children. This again underlines the importance of improving instrumental methods in children with disorders of the digestive system.

The prevalence of multi-drug resistance (MDR) in separate territories of the Irkutsk region is different, which is as-sociated with the geographical features and the availability of microbiological research facilities. Between 2003 and 2015, the proportion of new TB cases with MDR increased in most of the territories of the region except “Large Cities” and the Buryat national district. In Large Cities of Irkutsk region and Buryat district MDR level is high, but the growth rate is insignificant. The area of “Major settlements along the railway” was characterized by an intensive increase in the proportion of first-time detected and previously treated TB patients with MDR. One reason for this phenomenon is the intense migration of the population. In “Northern areas” there was an accumulation of MDR among contingents associated with the empirical assignment of anti-TB drugs and low availability of microbiological testing. In the “Rural areas” MDR was rarely identified due to troubles with microbiological diagnostics.

Objective of research: the analysis of Coenurus cerebralis found in the brain of a bison from Prioksko-Terrasny Nature Biosphere Reserve of the Moscow region. Materials and methods. We have conducted the euthanasia and dissection of the brain of a bison calf due to manifestation of clinical neurological symptoms. Results and discussion: After brain dissection, a strange large dumb-bell shaped vesicle was revealed in the brain tissue. On the inner surface of the vesicle the protoscolexes of helminthwere found. The surrounding brain tissue was significantly atrophied, cerebral meninges were swollen, and fissures were smoothed. To confirm the species belonging of the parasite, a part of surface with 50 protoscolexes was fed to a 6 mo. aged dog. 2,5 months later, Тaenia multiceps proglottids were revealed in dog’s feces, which confirmed the belonging of Coenurus cerebralis. It was found, that the bison might be one of the intermediate hosts for this helminth.