These data showed that an association between vitamin D insufficiency and low BMD was more prominent in elderly subjects with sarcopenia.

BACKGROUND AND PURPOSE: Stent-assisted coiling of intracranial aneurysms arising from small vessels (# 2.0 mm) is a common procedure. However, data regarding its treatment outcomes are scarce. This study evaluated the clinical and radiologic outcomes of stent-assisted coiling using low-profile stents for aneurysms of small parent arteries. MATERIALS AND METHODS:From November 2015 to October 2020, sixty-four patients with 66 aneurysms arising from parent arteries of #2.0 mm were treated with stent-assisted coiling using a Low-Profile Visualized Intraluminal Support Junior (LVIS Jr) or the Neuroform Atlas stent in a single institution. The clinical and radiologic data were retrospectively reviewed, and the risk factors for procedure-related complications were evaluated. RESULTS:The LVIS Jr and Neuroform Atlas stents were used in 22 (33.3%) and 44 (66.7%) cases, respectively. Technical success was achieved in 66 cases (100%). Immediate postprocedural aneurysm occlusion grades assessed by the Raymond-Roy occlusion classification were I (57.6%), II (19.7%), and III (22.7%), respectively. Procedure-related complications occurred in 10 cases (15.2%), with 8 thromboembolic complications (12.1%) and 2 hemorrhagic complications (3.0%). Procedure-related morbidity was 4.5% without mortality. On multivariate analysis, current smoking (odds ratio ¼ 7.1, P ¼ .021) had a statistically significant effect on procedure-related complications.CONCLUSIONS: Stent-assisted coiling of intracranial aneurysms with low-profile stents in small vessels (# 2.0 mm) had a 100% success rate and a 15.2% overall complication rate with 4.5% morbidity. Current smoking was a significant risk factor associated with procedure-related complications.

KeyWordsColumn liquid chromatography NMR spectroscopy ChTral solvatTng agent 18 Crown 6 tetracarboxylic acid SummaryThe enantTomers of dTphenylalanTne (DPA) were well separated by chiral HPLC and NMR spectroscopy on the chiral statTonary phase (CSP) derTved from (18-crown-6)-2,3,11,12-tetracarbaxylic add (18-C-6-TA). The chromatographTc parameters such as separation factors and retention times were greatly influenced by the mobile phase conditions. The (+) 18 C 6IA used Tn the CSP was also employed as a chTral solvating agent for the enantTodiscrTmTnatTon of the D?A enantTomers by NMR spectroscopy. The proton of the DPA analyte showing the chemical shift nonequTvalenoes was used Tn determinTng the enantTomeric composTtion of the analyie.no alcohols and quinolone antibacterials. More recently, we reported detailed NMR studies on the chiral recognition mechanism of phenylglycine and phenylglycine methyl ester using (+)-18-C-6-TA as a chiral selector [9]. For the development of potent thrombin inhibitors, diphenylalanine (DPA), possessing a unique amino acid structure, has been used as an essential chiral precursor [10 12]. During the preparation of intermediates of these compounds, the determination of the enantiomeric purity of prepared DPA was needed. In this study we demonstrate the liquid chromatographic resolution of DPA using the 18-C-6-TA-derived CSP. We also show that the chiral selector, 18-C-6-TA used in the CSP, can be employed for resolution of DPA as a chiral solvating agent (CSA) by NMR spectroscopy [ 13,14].

Application potential of ZnO nanowires grown by MOCVD for atomic force microscope (AFM) probes was evaluated by predicting numerically their structural performances in terms of flexural stiffnesses and natural frequencies. Estimated properties of the nanowires suggested that they are structurally compatible with typical AFM cantilevers while maintaining mechanical stability during operation and they are therefore promising candidates for high aspect ratio probes.