Explicitly, young professionals are at risk of facing the rigorous dilemmas of job burnout through victimization due to poor job performance in a multifaceted environment. Therefore, the present study aims to identify the relationship between innovative behavior, the joint role of in-role behavior and task interdependence, victimization, and job burnout in healthcare organizations. However, a cross-sectional sample of 330 early career healthcare professionals from public and private hospitals operating in Pakistan is included in the analysis which provides evidence for the generalizability of the research findings. Partial least structure equation modeling is implemented to test the proposed model of job burnout. Consequently, study results show a significant level of job burnout through victimization, leading to distress mental health, innovativeness, and job performance of early careers. However, investigation of job burnout has disclosed severe consequences which give meaningful direction for healthcare managers, to strengthen creative capabilities and performance of early careers by implementing useful strategies to reduce job burnout and other factors linked to job burnout.