Background Headache is as old as human history and has been able to report, and the first descriptions were found in Greece and Mesopotamia. Objective Our objective was to know the date of the first description of ICHD‐3 headaches, with their respective author. Methods We searched for articles that addressed the historical aspects of primary and secondary headaches and painful cranial neuropathies. Results Twenty‐seven different headaches were analyzed according to the occurrence of their first description, with the respective author and country of origin. Conclusions The knowledge of the first description of ICHD‐3 headaches, with their respective author, showed us how and when the different headaches appeared over the years.

IntroductionPossibly fibromyalgia and migraine share similar pathophysiological mechanisms, generatingan imbalance of neurotransmitters involved in pain modulation, with increased neuronal excitability. The association between these two conditions is frequent, increasing the disability of both.ObjectivesWe aimed to review articles published in the last 20 years about the presence of fibromyalgiain patients with migraine and to analyze the quality of life of these patients.MethodsBased on a literature search in the major medical databases and using the descriptors “migraine” and “fibromyalgia” we include articles published between 2001 and 2021. We found 387 articles, but only five met the inclusion criteria.ResultsIn five articles analyzed, 429 patients with migraine were found, in which fibromyalgiawas present in 31.5% of them, predominantly in women (p<0.0001). In this association, there was a higher risk for depression and worse quality of life.ConclusionsThe association of fibromyalgia in patients with migraine is frequent, increasing the disabilityof these two diseases and generating great social impact. Knowledge of this association and the management of its consequences are necessary in medical practice.

IntroductionPropranolol was the first non-selective beta-adrenergic blocker to be developed. Initially it was used in the treatment of cardiovascular diseases, but since the 60's it has been used in the prevention of migraine.ObjectiveThe objective of this study was to know the history of propranolol and its use as a migraine prophylactic.MethodsThis study was an integrative literature review using articles with historical data on propranolol, from its origin in cardiology to its indication in the preventive treatment of migraine.ResultsPropranolol was described in 1962 for the treatment of cardiovascular diseases. In the same decade, it was prescribed for the preventive treatment of migraine and, recently, included in the consensus of the Brazilian Headache Society.ConclusionAlthough propranolol was initially synthesized for the treatment of heart disease, it has proved to be an effective drug in preventing migraine attacks.

Introduction: Hypnic headache is a rare primary headache disorder that occurs during sleep. Its pathophysiology is uncertain, but hypothalamic dysfunction is hypothesized. It is usually a primary headache, but it can have secondary causes. Objectives: We aimed was to review articles published in the last 34 years on hypnic headache and analyze secondary cases. Methods: Based on a literature search in the major medical databases and using the descriptor “hypnic headache” we included articles published between 1988 and 2020. Of the 359 patients found, only 18 met the inclusion criteria and were analyzed. Results: We found 18 patients (6 men and 12 women) with secondary hypnic headache. The mean age of patients was 58.7±15.0 years, ranging from 20 to 84 years. The causes of hypnic headache were attributed to cranial vascular disorder (five), to non-vascular intracranial disorder (six), to a substance or its withdrawal (three) and to disorder of homoeostasis (four). Conclusions: Although most cases of hypnic headache are primary, some symptomatic cases are described in the literature.

IntroductionThere are some physiological situations in which the individual may experience headache, such as to sleep, to cough and to love. In the first situation, "to sleep", the patient does not have headache when awake, but is awakened by pain during sleep; in the second, the act of "to cough" is a trigger for the onset of pain and finally, "to love," here, meaning sexual intercourse, can be a headache trigger.ObjectiveTo review the epidemiological, pathophysiological aspects and therapeutic management of headaches that arise when sleeping, coughing and having sexual intercourse.MethodA narrative review of literature including case reports and clinical trials were carried out. The articles were systematically obtained and assessed by the authors.ResultsThree primary forms considered rare were identified: hypnic headache, primary cough headache and primary headache associated with sexual activity. Hypnic headache occurs only during sleep, predominantly in women after 50 years of age. It was described in 1988 by Raskin, and has a prevalence ranging from 0.07% to 0.22%. Primary cough headache is triggered by coughing or another Valsalva maneuver and is more common in men over40 years of age. It was first described by Jules Tinel and has a prevalence of 0.4% to 1.2%. Primary headache associated with sexual activity occurs during sexual intercourse. It is more frequent in men after 40 years of age. It was described in the second century of the Christian era, by the Persian physician Avicenna. Its prevalence ranges from 0.9% to 1.6%.ConclusionPrimary headaches in the "to sleep", "to cough", and "to love" group are rare. They predominate in men, after 40 years of age, are of short duration, can be primary or secondary and have a therapeutic response to indomethacin.