The original article was inadvertently published with an inaccurate application rate of the composted pig manure. The correct application rate is shown here: N, P, K and organic manure were applied in the form of urea (120 kg N ha-1 per year), calcium superphosphate (60 kg P 2 O 5 ha-1 per year), KCl (120 kg K 2 O ha-1 per year), and composted pig manure (30 t ha-1 per year), respectively. Plant Soil (2010) 326:523

Graphene oxide (GO) was investigated as a potential drug-delivery system due to its special properties and biocompatibility. Thus far, little has been done to use GO as a photosensitive drug-delivery system and to explore its anticancer activity in vitro in photodynamic therapy applications. Here, a novel GO-hypocrellin A (GO-HA) hybrid was prepared by a simple noncovalent method and its photodynamic activity was studied for the first time. The results showed that an efficient loading amount of HA on GO was as high as 1.0 mg mg(-1) and the stability of the hybrid was superior to that of the free hypocrellin A in aqueous solution. Furthermore, GO-HA can be excited by irradiation with light of appropriate wavelength to generate singlet oxygen, and in vitro experiments illustrated that GO-HA was efficiently taken up by tumor cells, and that light irradiation of such impregnated cells resulted in significant cell death. Thus, these properties of GO-HA could possibly make it especially promising for use in clinical photodynamic therapy.

No abstract

No abstract

No abstract