Background & Aims: Growing evidence has shown that M2-PK is involved in cancer diagnosis and prognosis. The overall diagnostic accuracy of the pyruvate kinase isoenzyme type M2 (M2-PK) in biliary tract carcinoma (BTC) remains controversial. We performed a meta-analysis to evaluate the diagnostic value of M2-PK for BTC.Methods: The online PubMed, Cochrane, Web of Science, and Embase databases were searched for eligible studies published until August 8th, 2017. The Quality Assessment for Diagnostic Accuracy Studies 2 (QUADAS-2) was used to evaluate study quality. All statistical analyses were conducted with Stata 12.0.Results: We included 7 studies from 5 articles with 410 patients with BTC and 438 controls. The pooled sensitivity, specificity, positive likelihood ratio (PLR), negative likelihood ratio (NLR), diagnostic odds ratio (DOR), and AUC for M2-PK in the diagnosis of BTC were 0.79 (95%CI 0.70-0.86), 0.81 (95%CI 0.71-0.88), 4.1 (95%CI 2.5-6.8), 0.26 (95%CI 0.16-0.41), 17.159 (95%CI 5.468-54.071), and 0.87 (95%CI 0.83-0.89), respectively. The same indicators assessed for CA19-9 were as follows: 0.70 (95%CI 0.62-0.77), 0.71 (95%CI 0.45-0.87), 2.38 (95%CI 1.2-4.73), 0.43 (95%CI 0.34-0.53), 6.28 (95%CI 2.4-16.44) and 0.73 (95%CI 0.69-0.77), respectively. Additionally, the diagnostic value of M2-PK varied based on characteristics of golden methods and different cut-off values.Conclusions: This meta-analysis showed that M2-PK had a better diagnostic accuracy for BTC compared with CA19-9, with moderate diagnostic performance. However, prospective studies are required to confirm its diagnostic value.

Conducting polymer – polypyrrole (PPy) microstructures were fabricated in an aqueous solution of dodecylbenzenesulfonic acid (DBSA) by electrochemical polymerization. The study implied the concentration of DBSA had great effect on the morphologies and conductivities of PPy microstructures. At lower DBSA concentration (0.2M), no obvious microstructures were generated. Increasing DBSA concentration, some novel “chayote-like”, “flower-like” microstructures were obtained by modulating electrochemical conditions. The growth process of microstructures was studied by scanning electron microscopy and relevant mechanism was discussed. Raman characterizations indicated that the microstructures were made of conductive PPy doped by DBSA.

Cu-Mn/Al2O3, Cu-Mn/TiO2and Cu-Mn/SBA-15 were prepared by incipient wetness impregnation. The activity of those catalysts for selective catalytic oxidation (SCO) of ammonia to nitrogen at low temperature (100°C~250°C) is not so satisfying. 5%Cu-5%Zr/TiO2has the highest NH3conversion and highest NO, NO2yield. 5%Cu-5%Mn/Al2O3is a promising NH3selective catalytic oxidation catalyst, but still needs further study. SBA-15 is a bad support for Cu-Mn. Al2O3-based catalysts and TiO2-based catalysts were also prepared by incipient wetness impregnation to sure the synergistic effect between transition metal. The results find the activity on Cu-Mn/Al2O3is better than Cu-Mn/TiO2, but NH3conversion on Cu-Zr/TiO2is rather well with high yield of NO. The role of supports and transition metals play in catalyst are discussed by a series of experiments. Key ward: SCO, NH3, transition metal, γ-Al2O3, TiO2, SBA-15

LiFePO4/C cathode material with particle size of 5~6 μm and tap density of 1.67 g•cm-3 was prepared based on spherical crystal FePO4•2H2O powders. The spherical crystal FePO4•2H2O powders were first prepared by a simple hydrothermal synthesis via the amorphous FePO4•2H2O solution maintained at 150°C for 12 h without any supplementary equipment. The produced LiFePO4/C powders exhibited the initial discharge capacity of 137 and 118 mAh•g-1 at 0.1 C and 0.5 C, respectively. The volumetric capacity of the spherical LiFePO4/C powders corresponded to 230 and 197 mAh•cm-3, which are remarkably higher than irregularity powders. The high-density spherical LiFePO4/C powders produced by this novel method can be considered as a very promising candidate in the high-power batteries.