Adverse drug reactions (ADR) are a significant cause of morbidity and mortality, often identified only post-marketingly. Improvement in current ADR reporting, including utility of underused or innovative methods, is crucial to improve patient safety and public health. Hospital-based monitoring is one of the methods used to collect data about drug prescriptions and adverse events. The aims of this study were to identify the most frequent ADRs recognized by the attending physicians, study their nature, and to target these ADRs in order to take future preventive measures. A prospective study was conducted over a 7-month period in an internal medicine department using stimulated spontaneous reporting for identifying ADRs. Out of the 254 admissions, 32 ADRs in 37 patients (14.56%) were validated from the total of 36 suspected ADRs in 41 patients. Female predominance was noted over males in case of ADRs. Fifty percent of total ADRs occurred due to multiple drug therapy. Dermatological ADRs were found to be the most frequent (68.75%), followed by respiratory, central nervous system and gastrointestinal ADRs. The drugs most frequently involved were antibiotics, anti-tubercular agents, antigout agents, and NSAIDs. The most commonly reported reactions were itching and rashes. Out of the 32 reported ADRs, 50% of the reactions were probable, 46.87% of the reactions were possible and 3.12% of the reactions were definite. The severity assessment done by using the Hartwig and Seigel scale indicated that the majority of ADRs were ‘Mild’ followed by ‘Moderate’ and ‘Severe’ reactions, respectively. Out of all, 75% of ADRs were recovered. The most potent management of ADRs was found to be drug withdrawal. Our study indicated that hospital based monitoring was a good method to detect links between drug exposure and adverse drug reactions. Adequate training regarding pharmacology and optimization of drug therapy might be helpful to reduce ADR morbidity and mortality.

Background: Surgery is one of medical interventions which can cause fear, anxiety, and stressed because of its effects toward the integrity of body and soul. Nurses have significant roles in any preoperative care which is helping patients to decrease preoperative anxiety by using complementary therapy. The use of music therapy as one of the complementary therapies is not common in Indonesia. Therefore, scientific studies to prove the role of this therapy to decrease the level of anxiety of pre-operative patients is needed. Objective: To investigate the effects of music therapy in reducing anxiety levels of preoperative patients. Methods: A quasy experimental study with pre-test and post-test design with control group was applied to 50 respondents from medical ward in Panembahan Senopati Hospital of Yogyakarta who met the inclusion criteria.Dara were then analyzed by using t-test statistical analysis. Results: The control group showed the increased value of anxiety level of0.8 without music intervention (t= - 1503, df = 24, p<.05), whereas the intervention group showed the decreased value of anxiety level of -5.52 (t=5.081, df=24, p<.05). Meanwhile the independent t-test results for both groups showed a significant difference between group (t= 3,373, df=48, p<.05). Conclusion: Music therapy has significant effect in reducing preoperative anxiety levels of patients. Keywords: anxiety, preoperative, music therapy

Aged people will experience several changes in all aspects of life including, physical, psychological, spiritual, and social. Their altered condition such as hearing deprivation, loss of vision, or fluctuating emotions will affect how the way they communicate with other family members. Thus, the family should be more concerned regarding this issue, unless they will have ineffective communication. Moreover, it may lead to trigger a conflict among family members. To unravel this problem, an education on effective communication for aged people using a module will help them to improve strategies for managing the elderly's communication problems. This activity involved 67 families with elderly and 7 health volunteers in Kelurahan Patangpuluhan Wirobrajan Yogyakarta. The result showed that education could elevate the score of effective communication among aged people, both family, and health volunteers. However, health volunteers had a higher average score than family

The most complaint symptom for post herniotomy patients is pain on the surgical site. Pain may affect patients' ability to mobilize and may attribute to prolonged length of stay in the hospital. Many complementary therapies have been used to decrease pain intensity for patients post-surgery, but warm compress intervention on post herniotomy pain has not been explored significantly. To investigate the effect of warm compress intervention on post herniotomy pain. The study used a pre-post test quasi-experimental with control group design. Sixteen post herniotomy adult patients of Wates Kulon Progo District General Hospital of Yogyakarta were recruited for each group. The intervention group was given warm compress interventions two times per day for two days. Pain intensity was assessed pre and post-intervention with the Numerical Rating Scale, while the control group only received regular analgetic. The researchers used the Wilcoxon Signed-Rank Test and Mann-Whitney U Test to compare pain intensity in each group and between groups.Fifteen out of 16 patients who received warm compress intervention rated decreased pain intensity as the rest did not experience any differences after the intervention (Z=-3.354, p=.001). Unlike the control group, only 3 out of 16 patients experienced declined pain intensity after two days of herniotomy when the rest did not encounter any changes (Z=-1.732, p=.083). The mean rank between intervention and control groups were significantly different (U=20.000, p=.000). Warm compress intervention is a non-invasive nursing intervention which is effective in reducing the pain intensity of post herniotomy patients.