No abstract

Based on the physiological nature of breast movement in exercising females, a sports bra made of fabric with dynamic moisture transfer properties was developed to improve female thermal comfort. This study aimed to investigate the effects of fabrics with dynamic moisture transfer properties on breast skin temperature, and the thermal physiological and psychological response of women while wearing the sports bra during exercise and recovery. Ten healthy women exercised in random order with two types of sports bra with or without the dynamic moisture transfer properties and then performed a 20-minute short-duration high-intensity exercise and rest to recover under thermoneutral conditions. Heart rate, body core temperature, skin temperature, body mass and thermal psychological subjective sensations were investigated during exercise and recovery. The results indicated that in the running state, the local breast skin temperatures of sports bra made of fabrics with dynamic moisture transfer properties (33.427 ± 0.087℃) are significantly lower than bras without these dynamic moisture transfer properties (33.964 ± 0.055℃) ( P < 0.01). During the exercise and recovery, the thermal psychological subjective sensation for the two types of fabrics were very similar, whereas the body mean skin temperature was revealed to undergo greater decreasing effects in sports bras made of fabrics with dynamic moisture transfer properties than those without the dynamic moisture transfer properties ( P < 0.05). These results provide novel information that usage of fabrics with dynamic moisture properties in sports bras could improve thermoregulation to benefit exercising women’s thermal comfort in terms of decreasing local breast skin temperature.

Antimicrobial peptides, produced by innate immune system of hosts in response to invading pathogens, are capable of fighting against a spectrum of bacteria, viruses, fungi, parasites and cancer cells. Here, a recombinant silkworm AMP Bmattacin2 from heterologous expression is studied, indicating a broad spectrum of antibacterial activity and showing selective killing ability towards skin and colon cancer cells over their normal cell counterparts. For the purpose of biomedical application, the electrospinning fabrication technique is employed to load Bmattacin2 into PLLA nanofibrous membrane. In addition to a good compatibility with the normal cells, Bmattacin2 loaded nanofibrous membranes demonstrate instant antibacterial effects and sustained anticancer effects. The cancer cell and bacteria targeting dynamics of recombinant Bmattacin2 are investigated. With these characteristics, PLLA/Bmattacin2 composite membranes have a great potential for developing novel biomedical applications such as cancer therapies and wound healing treatments.