Background
Recent studies evaluated the efficacy of a collagen membrane (Bio‐Gide) to promote root development in regenerative endodontics (REPs). However, the influence of etiology and tooth type on the results was not assessed.
Aims
To evaluate the quantitative and qualitative effect of a collagen membrane (Bio‐Gide), with and without the effect of etiology and tooth type, in promoting root development in immature teeth after REPs.
Design
Eighty nonvital immature teeth were divided randomly into two groups (40 teeth in each group). REPs were performed with (experimental group) and without (control group) a collagen membrane. All teeth were subjected to regular clinical and radiographical follow‐up.
Results
Seventy‐six teeth were included in the final analyses. The average follow‐up periods were 33.1 ± 21.8 months for the control group and 28.1± 18.6 months for the experimental group. Quantitative analysis of root development in the experimental group showed a greater increase in dentin wall thickness in the middle one‐third of the root compared to the control group, with or without the effect of etiology and tooth type. Six types of root development were observed. There was no significant difference in the type of tooth development between the two groups.
Conclusion
The use of a collagen membrane could promote an increase in dentin wall thickness in the middle one‐third of the root, and it had no significant effect in terms of the type of subsequent root development.
Aim
This study aimed to evaluate the characteristics of root canal calcification after regenerative endodontic procedures (REPs) during long‐term follow‐up.
Design
Data of children who underwent REPs and were followed up for >3 years in the Department of Pediatric Dentistry, Peking University School and Hospital of Stomatology, Beijing, China, from January 2013 to January 2019, were collected. All the patients were treated by the protocol of REPs based on the American Association of Endodontists (AAE) protocol. A total of 91 teeth of 54 boys and 37 girls (average age 10.4 ± 1.9 years) with follow‐up duration >3 years were included. The follow‐up duration ranged from 36 to 92 months (average, 53.2 ± 13.4 months). The prevalence, contributing factors, and long‐term prognoses of root canal calcification after REPs are discussed. Independent t‐test and χ2 test were used for statistical analysis.
Results
The incidence of root canal calcification was 78% (71/91). The use of calcium hydroxide paste was significantly correlated with the occurrence of root canal calcification (p < .05). Some teeth showed aggravation of calcification with time; however, not all teeth showed calcification after longer follow‐up duration.
Conclusions
Teeth treated with REPs had a relatively high probability of root canal calcification detection during the long‐term follow‐up. The occurrence of calcification is related to the use of calcium hydroxide paste but does not affect the long‐term prognosis of teeth.
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