The urban agglomeration in the middle reaches of the Yangtze River, which is the second largest urban agglomeration in China, represents a typical land space range of ecological vulnerability in China. Large differences occur in economic development mode between resource- and non-resource-based cities in this basin area. Accurate identification of the evolution and regional differences in the production-living-ecological space (PLES) is very important in order to elucidate the development and utilization of land space in the region. At present, relevant research has largely focused on the classification and determination of PLES temporal and spatial patterns. Temporal and spatial pattern research has mainly considered a single scale of administrative division, whereas fewer studies have analyzed the temporal and spatial patterns and regional differences in the PLES in ecologically fragile natural watersheds. Therefore, based on PLES classification, the regional differences in the PLES between two types of cities in the basin are measured via the Theil index and exploratory spatial data analysis (ESDA). First, the ecological space (ES) of these two types of cities in the urban agglomeration in the middle reaches of the Yangtze River is compressed by the production space (PS) and living space (LS), in which the ES of resource-based cities is compressed for a longer period, and the phenomenon involving PS compression by the LS and ES mainly occurs in non-resource-based cities within the urban agglomeration in the middle reaches of the Yangtze River. Second, the PLES of these two types of cities exhibits the characteristics of spatial aggregation, and high- and low-density areas of the PLES remain relatively stable. Third, the regional differences in the PLES of the urban agglomeration in the middle reaches of the Yangtze River mainly originate from intraregional differences. The PLES of these two types of cities in the urban agglomeration in the middle reaches of the Yangtze River is more sensitive to changes in economic development than to those in the population distribution.
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