The role of pharmacists in the implementation of pharmaceutical care has been shown to improve the outcome of therapy in hypertension patients in various countries. This study aimed to implement pharmaceutical care for hypertension patients and determine its impact on the incidence of drug-related problems (DRPs) and clinical outcomes of hypertension patients in Puskesmas Lubuk Pakam. This study used a comparative experimental method before and after the intervention of 73 hypertension patients in March-August 2021. Identification of the of DRPs was using the PCNE V9.00 standard and blood pressure values were obtained from direct examination of patients. Data were analyzed using the Wilcoxon Signed-Rank test. The results showed that the average DRPs incidence was significantly reduced after the intervention (observation, interview, and education) on the hypertension patients. The average blood pressure before intervention was 154.38 ± 16.20 mmHg and after intervention became 144.04 ± 15.94 mmHg (p value = 0.000). Based on the results of the study, it can be concluded that the application of pharmaceutical care can reduce the incidence of DRPs and improve clinical outcomes in hypertension patients in Puskesmas Lubuk Pakam.

Bean robusta coffee contains polyphenol compounds which are useful as antioxidants. Antioxidants can inactivate the development of oxidation reactions, by preventing the formation of free radicals. Robusta coffee bean plant (Coffea canephora) is an ingredient that can be formulated into lotion preparations. Cosmetic lotion aims to remove dead skin cells, brighten the skin and soften the skin. This research is to make lotion preparations from robusta coffee bean extract (Coffea Canephora) . This research uses pure experiment. Robusta coffee beans are extracted by maceration process. The lotion formulation is made with variations of robusta coffee bean powder (Coffea Canephora) with a concentration of 2%, 3%, and 4%. The characteristic test includes organoleptic test, homogeneity test, Ph test, and irritation test. The purpose of this study was to determine the lotion formulation for robusta coffee bean extract (Coffea Canephora). The results of the lotion test had a homogeneous concentration of 2%, 3% and 4%, light brown to blackish brown, with a distinctive smell of coffee. The ph lotion test had a PH of 5 in all formulations on the blank had a PH of 6. The irritation test on the lotion preparation showed no erythema and edema in 5 volunteers. From all the tests carried out, the lotion formulation has good characteristics.

Salah satu tanaman yang sering dijadikan obat adalah daun Talas  (Colocasia esculanta L.). Daun talas memiliki kandungan senyawa flavonoid, alkaloid, saponin dan tannin yang memiliki kemampuan untuk menghambat pertumbuhan bakteri. Eschericia coli  adalah salah satu jenis bakteri yang dapat menyebabkan infeksi pada pencernaan. Salah satu tujuan penelitian ini untuk mengetahui aktivitas antibakteri daun talas dengan konsentrasi yang paling efektif dalam menghambat bakteri Eschericia coli. Penelitian ini adalah penelitian eksperimental murni. Daun talas aktivitas antibakteri dilakukan dengan metode difusi cakram. Penelitian dilakukan dengan 3 variasi konsentrasi yang berbeda. Hasil penelitian menunjukkan bahwa ada aktivitas antibakteri pada setiap konsentrasi. Kesimpulan pemberian aktivitas daun talas dengan konsentrasi 15%, 25%, dan 35% memberikan daya hambat pertumbuhan bakteri paling efektif dengan kosentrasi 25%, 35% yang termasuk dalam kategori kuat. Saran diharapkan kepada peneliti selanjutnya dapat melakukan uji terhadap bakteri lain dan membuat formulasi dari ekstrak daun talas.