Purpose Stationary computed tomography (s‐CT) conceptually offers several advantages over existing rotating gantry‐based CT. Over the last 40 yr, s‐CT has been investigated using different technological approaches. We are developing a s‐CT system specifically for head/brain imaging using carbon nanotube (CNT)‐based field emission x‐ray source array technology. The noncircular geometry requires different assessment approaches as compared to circular geometries. The purpose of the present study is to investigate whether the CNT source array meets the requirements for stationary head CT (s‐HCT). Methods Multiple prototype CNT x‐ray source arrays were manufactured based on the system requirements obtained from simulation. Source characterization was performed using a benchtop setup consisting of an x‐ray source array with 45 distributed focal spots, each operating at 120 kVp, and an electronic control system (ECS) for high speed control of the x‐ray output from individual focal spots. Due to the forward‐angled geometry of the linear anode, the projected focal spot shape is expected to vary at wide angle views. A pinhole method was implemented to determine the effective focal spot size (FSS) in the imaging plane at a range of angular viewpoints with a flat panel detector. The output spectrum and half value layer (HVL) were also evaluated for a range of viewing angles to characterize the beam quality across the fan‐beam. Dosimetry was performed on a simulated scan to evaluate total exposure. Results The prototype CNT x‐ray source array demonstrated adequate specifications for a s‐HCT imaging machine. The source array was operated at 120 kVp with long‐term stability over a full year of regular laboratory use. Multiple cathode current measurements were used to confirm submicrosecond accuracy with regards to exposure time and subsequently dose control. All 45 focal spots were measured with an average value of 1.26 (±0.04) mm × 1.21 (±0.03) mm (equivalent to IEC 1,0). The x‐ray spectrum was found to be appropriately filtered based on sources used in existing rotary CT systems. A stable and reliable output of 0.04 mAs per emitter and a resulting dose of 0.015 mGy per projection were observed over several months of rigorous phantom imaging. Dose per projection was regulated by the ECS and measured with ±0.5% tolerance. Conclusions The CNT x‐ray source array was found to meet the requirements for the proposed stationary head CT scanner, with regard to FSS, beam quality, and dose precision. The remaining challenges are related to the overall system design of a nonrotating CT scanner with distributed sources. The next phase of the project will incorporate multiple CNT source arrays with multirow detectors in a proof‐of‐concept study and analysis of a fully functional s‐HCT system.
Cone beam computed tomography (CBCT) is now widely used in dentistry and growing areas of medical imaging. The presence of strong metal artifacts is however a major concern of using CBCT especially in dentistry due to the presence of highly attenuating dental restorations, fixed appliances, and implants. Virtual monoenergetic images (VMIs) synthesized from dual energy CT (DECT) datasets are known to reduce metal artifacts. Although several techniques exist for DECT imaging, they in general come with significantly increased equipment cost and not available in dental clinics. The objectives of this study were to investigate the feasibility of developing a low-cost dual energy CBCT (DE-CBCT) by retrofitting a regular CBCT scanner with a carbon nanotube (CNT) x-ray source with dual focal spots and corresponding low-energy (LE) and high-energy (HE) spectral filters. A testbed with a CNT field emission x-ray source (NuRay Technology, Chang Zhou, China), a flat panel detector (Teledyne, Waterloo, Canada), and a rotating object stage was used for this feasibility study. Two distinct polychromatic x-ray spectra with the mean photon energies of 66.7keV and 86.3keV were produced at a fixed 120kVp x-ray tube voltage by using Al+Au and Al+Sn foils as the respective LE and HE filters attached to the exist window of the x-ray source. The HE filter attenuated the x-ray photons more than the LE filter. The calculated post-object air kerma rate of the HE beam was 31.7% of the LE beam. An anthropomorphic head phantom (RANDO, Nuclear Associates, Hicksville, NY) with metal beads was imaged using the testbed and the images were reconstructed using an iterative volumetric CT reconstruction algorithm. The VMIs were synthesized using an image-domain basis materials decomposition method with energy ranging from 30 to 150keV. The results were compared to the reconstructed images from a single energy clinical dental CBCT scanner (CS9300, Carestream Dental, Atlanta, GA). A significant reduction of the metal artifacts was observed in the VMI images synthesized at high energies compared to those from the same object imaged by the clinical dental CBCT scanner. The ability of the CNT x-ray source to generate the output needed to compensate the reduction of photon flux due to attenuation from the spectral filters and to maintain the CT imaging time was evaluated. The results demonstrated the feasibility of DE-CBCT imaging using the proposed approach. Metal artifact reduction was achieved in VMIs synthesized. The x-ray output needed for the proposed DE-CBCT can be generated by a fixed-anode CNT x-ray source.
Purpose: The invention of carbon nanotube (CNT) x-ray source arrays has enabled the development of novel imaging systems, including stationary tomosynthesis and stationary computed tomography (CT) with fast data acquisition, mechanically robust structures, and reduced image blur from source-detector motion. In this work, we report the results of simulation studies of potential system configurations for a stationary head CT (s-HCT) using linear CNT x-ray sources and detector arrays.Approach: We explored s-HCT configurations that utilize one, two, and three linear CNT source arrays. Simulations were implemented using three digital phantoms with both CPU and GPU computing. Sinogram coverage was used for qualitative evaluation of the CT projection collection efficiency for each configuration. A modified low-contrast Shepp-Logan (SL) phantom was implemented for image quality assessment using quantitative metrics. Different iterative reconstruction (IR) methods were compared with both qualitative and quantitative assessments.Results: Sinogram coverage of s-HCT configurations was sensitive to the number of CNT source arrays and geometry. The simulations suggest that a s-HCT configuration with three planes gives near complete sinogram coverage. Such a configuration enables accurate reconstruction of the low-contrast SL phantom and considerably diminished artifacts caused by the system geometry.Conclusions: An optimized s-HCT system configuration with three linear CNT x-ray source arrays is feasible. IR algorithms can diminish artifacts caused by sparse and asymmetrical scans. The proposed s-HCT system configuration is currently under construction.
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