The first synthesized derivative of (3¢,4¢-methylenedioxyphenyl)-6,7-methylenedioxy-1,2,3,4tetrahydroquinoline, conventionally designated F-29, showed neuroleptic properties-they have hypothermic, cataleptogenic, less pronounced suppression of motor activity, lack of central αadreno-and M-anticholinergic action and less toxic in severity comparable to the activity of a more close analogue of the neuroleptic haloperidol, which has motor and autonomic disorders [1], which F-29 lacks.

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