Purpose The aim of this study was to determine whether choroidal thickness (CT) increases at the time of exudative recurrence in diabetic patients with unilateral diabetic macular oedema (DME) treated with intravitreal injections of anti‐VEGF or dexamethasone. Methods A real‐life, prospective, two‐centre study was conducted over a 9‐month period investigating diabetic patients presenting with unilateral DME treated with anti‐VEGF or dexamethasone intravitreal injections, and CT was measured manually, using the enhanced depth imaging module of the spectral domain optical coherence tomography. Choroidal thickness (CT) was measured in the morning, in both the affected and healthy eye of each patient at two timepoints: when the macula was ‘dry’ (T0) and at the time of exudative recurrence (T1). Results A total of 51 patients with unilateral DME were included. Mean CT in the affected eye was significantly thicker at the time of exudative recurrence (210.8 ± 44.1 μm at T0 versus 238.0 ± 49.0 μm at T1, p < 0.001). There was no significant variation in CT in the fellow eye (214.4 ± 52.3 µm at T0 versus 218.9 ± 53.4 µm at T1, p = 0.53). The type of intravitreal injection, the number of injections and the CT at T0 had no influence on the change in CT. Conclusion This study found that CT increased significantly in the affected eye at the time of recurrence of DME treated with anti‐VEGF or dexamethasone injections. Choroidal thickness (CT) could constitute an interesting new indicator for monitoring patients with DME.

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Purpose Surgical treatment of epiretinal membrane (ERM) have been facilitated by use of dyes such as brilliant blue G (BBG) whose harmlessness by intravitrael injection have been fully reported. Methods We describe the case of a seventy‐two year old female patient addressed for surgical treatment of left idiopathic ERM that caused metamorphopsia and a decrease of visual acuity. Pars plana vitrectomy and ERM peeling staining with BBG was performed. Results During the procedure, an unusual complication occurs: intraretinal BBG infiltration. The area was limited (under a disc diameter) located in macular area, in temporal and superior to the fovea; the infiltration reached all retinal layers according to our OCT images. A defect in retina nerve fiber layer seems to be the origin of that staining. No damage in the field or in fluorescein and indocyanine angiography were observed. A progressive resorption of the staining appeared with atrophy of the inners retinal layers as aftereffect. Visual acuity reached 9/10 Pa2 a month and a half after the surgery. Conclusion In spite of the benefits of vital dyes in vitreoretinal surgery which are widely used, this case remains us the damage that can occur.