• Transfusion was associated with increased cancer recurrence and mortality in ovarian cancer patients. • Transfusion was associated with higher postoperative complication rates and longer hospitalization stays. • Transfusion was associated with more postoperative fluctuations in systemic inflammatory markers.

a b s t r a c tPurpose: To investigate the preferred and actual participation levels of colorectal cancer patients and their families in treatment decision-making. Methods:A cross-sectional survey was conducted using a questionnaire administered to colorectal cancer patients hospitalized in the general surgical wards in two of the upper first-class hospitals in Beijing between February and July 2013.Results: A total of 113 questionnaires were analyzed. For the families of colorectal cancer patients, the concordance rate of their preferred and actual participation levels in treatment decision-making was 60.2% and 62.8% for the patients themselves. Patients with stoma and male patients preferred a passive role compared to those without stoma and female patients (x 2 ¼ 7.978, p < 0.05; x 2 ¼ 9.854, p < 0.05).Conclusions: Over 40% of colorectal cancer patients preferred a passive role in treatment decision-making. We suggest that communication between physicians and patients should be strengthened to accommodate the patient's desired level of involvement.

hegmatogenous retinal detachment (RRD) is the most common retinal emergency, carrying an annual incidence of 6.3 to 17.9 per 100 000 population, and is one of the most common indications for vitreoretinal intervention. 1,2 Surgical techniques and maneuvers used to repair RRD have evolved over decades such that high rates of retinal reattachment are currently achieved with pars plana vitrectomy (PPV), scleral buckle (SB), pneumatic retinopexy (PR), or combinations thereof. [3][4][5] Randomized clinical trials (RCTs) provide the best evidence to guide surgeons in the selection of interventions to optimize success for patients. [6][7][8][9] When comparing surgical procedures, it is important that these interventions are evaluated comprehensively with regard to their potential harms as well as their effectiveness. 10 There is evidence that the reporting of complications in clinical trials across many surgical and medical specialties lacks sufficient quality and consistency. [11][12][13][14][15] For example, although RCTs commonly report complication fre-quency, data on severity of complications are often lacking. [16][17][18] While classification systems for severity of surgical complications have been proposed and used in fields such as general surgery, neurosurgery, and urology, [19][20][21][22][23] to our knowledge, these have not been incorporated into ophthalmic RCTs. In response to this need, in 2018, Sii et al 24 published a grading system for complications of glaucoma surgery.With this in mind, the purpose of the study was to reach consensus among an international group of vitreoretinal surgeons on severity scores for complications of RRD surgery and to generate a classification system for quantifying and reporting severity of complications of retinal detachment surgery (CORDS). MethodsThree authors (Z.Y.X., N.L., and A.A.B.) generated first a preliminary list of complications of RRD surgery using a textbook IMPORTANCE Quantifying severity of complications in rhegmatogenous retinal detachment (RRD) surgical trials is needed. A consensus classification system will help surgeons to more effectively compare harms of different surgical techniques.OBJECTIVE To develop a new consensus-based classification to quantify severity of complications of RRD surgery. DESIGN, SETTING, AND PARTICIPANTSA comprehensive list of complications was developed followed by a Delphi consensus survey of international vitreoretinal surgeons. The survey was conducted in 17 countries in mainland Europe, the United Kingdom, the United States, Asia, South Africa, and Australia. Seventy vitreoretinal surgeons were invited to take part in the Delphi survey; 45 agreed to participate. Participants were selected through boards/members lists of retinal societies. Data were analyzed between April 2019 and August 2019. MAIN OUTCOMES AND MEASURESConsensus-derived classification of complications of RRD surgery, according to their severity.RESULTS Forty-three of 45 vitreoretinal surgeons who agreed to participate in the Delphi survey completed round 1...

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