The piezoelectric materials with excellent bioactivity have attracted more attentions recently and have broad potential applications in tissue engineering. In this article, the barium titanate (BT) particles were filled into the polycaprolactone (PCL)/calcium sulfate whisker (CSW) (15 wt%) composites to prepare the PCL/CSW/BT ternary composites. Due to the reinforcement synergy between the CSWs and the BT particles, the mechanical properties of the ternary composites were increased by 50% compared with the PCL/BT binary composites. The piezoelectric coefficient of the ternary composites is still in the range of natural bone. The ternary composite can promote the adhesion and proliferation of cells. The composites in this study have potential applications in tissue engineering.
Glutathione (GSH) capped CdTe quantum dots (QDs) with photoluminescence quantum yields of 61% and the maximum emitting at 601.2 nm were prepared in water phase. Giant unilamellar CdTe quantum dot vesicles (GUVs-CdTe), with diameters larger than 1.5 m, were obtained using lower-pressure evaporation techniques with soybean lecithin. Compared with other QD liposomes, the entrapment efficiency of GUVs-CdTe for QDs has been significantly improved to 86.3%. After GUVs-CdTe were injected into mice through the tail vein, the fluorescence microscopy of tissue sections showed that GUVs-CdTe could not pass through the blood-brain barrier and air-blood barrier, which were removed mostly by the reticuloendothelial system and were widely distributed in the spleen and the liver. This behavior is the same as the character of the metabolic pathway of giant unilamellar vesicles by intravenous injections in mice.
quantum dots, giant unilamellar quantum dot vesicles, metabolic pathway
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