Relevance. Multiple sclerosis (MS) is a chronic progressive neurodegenerative autoimmune disease of the central nervous system, affecting mainly people of working age and leading to disability. Since this disease is a frequent cause of persistent disability, the importance and at the same time insufficiency of research in the field of regional specific programs related to disability due to MS is noted. Aims. To study the dynamics and features of the formation of primary and repeated disability due to MS among various age groups of the population, taking into account gender characteristics and severity of disability in Moscow in 2014–2021. Materials and methods. The study used examination materials of persons over 18 years of age with MS, collected in an electronic database of medical and social expertise (ITU) of the Federal State Institution "ITU Main Bureau for Moscow", acts, protocols of ITU, static f-088/06 on the re-examination of RS. Results. The last 8 years have been characterized by a decrease in general disability due to MS, with a decrease in the number of persons recognized as disabled for the first time (VPI) and an increase in the number of persons re-recognized as disabled (PPI). There is a drop in the proportion of disabled people of the first and second disability groups with an increase in the third group. In the structure of VPI and PPI due to MS, persons of working age prevailed with a slight decrease in the group of PPI. The gender structure was dominated by female persons. Conclusion. The study of indicators of disability due to MS among various population groups in modern conditions is of great importance for monitoring the level of disability of patients and maintaining a socially active life of the patient.

Diseases of the blood and hematopoietic organs are one of the urgent medical and social problems. The effectiveness of the rehabilitation measures carried out depends on their compliance with functional disorders and the degree of disability associated with them. Aim. To study the dysfunction of the disabled person’s body and, based on them, to assess the limitation of vital activity and the degree of their severity. Material and methods. The study was generated in xlsx format and uploaded to the environment for statistical data analysis (https:www.r.project.org) using methods: documentary, data copying (184 units). Data processing and analysis were performed using scripts. For continuous normally distributed variables, the average value, the standard deviation, were calculated when comparing two groups of studies — the t–criterion, when comparing several groups — the ANOVA. Medians, 1st and 3rd quartiles were calculated for continuous abnormally distributed variables, and when comparing groups, the Kruskall-Wallis criterion was used. Absolute and relative frequencies were calculated for categorical variables, and when checking the conjugacy tables of 2x2 sizes, the Chi-square criterion or the Fisher criterion was used. Spearman’s rank correlation index was calculated for each pair of categorical variables. The significance level when testing statistical hypotheses was assumed to be 0.05. Results. It was found that in patients with blood and hematopoietic organs diseases, the greatest proportion in the structure of impaired functions were violations of the functions of the blood system and immunity, cardiovascular system, neuromuscular, skeletal and movement-related (statodynamic) and total functions, the severity of which, as a rule, was moderate. In the structure of restrictions of vital activity, the following restrictions of vital activity were determined: self-service abilities of the 1st degree, self-locomotion of the 1st degree and work activity of the 1st degree. Conclusion. Expert-rehabilitation diagnostics based on samples of different numbers and nosology among persons who have passed examination at the ITU bureau, allows us to form an idea of the amount of rehabilitation measures required for them, including in the conditions of assessment according to the requirements of the International Classification of Disorders, Disability and Social Insufficiency.The expert-statistical assessment of this contingent of disabled people allows us to predict the volume of examinations, to assume a prognosis for the course of diseases and to plan the volume of medical and rehabilitation care.

The article presents an analysis of the formation of general disability among persons older than working age due to diseases of the nervous system in Moscow. Introduction. Disability among the population – one of the most important medical and social problems – is an integral indicator. The purpose of the study is to study the patterns of the formation of general disability. Materials and methods. The study is solid for 2012–2018, using statistical forms of observation: form 7-sobes, statistical collections of THE Federal Security Service of the Russian Ministry of Labour. Research methods – excavation of information, descriptive statistics (absolute, extensive, intense indicators, series of dynamics, reliability assessment (average error). The results of the study. There has been an increase in the overall number of disabled people with a more pronounced growth rate in Moscow compared to the Central Federal District and the Russian Federation. The structure of general disability due to diseases of the nervous system was dominated by re-recognized persons with disabilities, but their share is lower than in the Central Federal District and the Russian Federation. The structure was dominated by disabled people in the third group with a tendency to increase their specific weight and disability, and there was a decrease in the proportion of disabled people in the I–II group and their levels. Conclusions. The total number of disabled persons among persons of older working age due to diseases of the nervous system in the dynamics of 2012–2018 has steadily increased, the growth rate was 18.6%, which is significantly higher than in the Central Federal District (4.1%) and the Russian Federation (8.2%). The structure was dominated by persons re-recognized as disabled, their share in the dynamics tended to increase, but the figure was lower than in the Central Federal District and the Russian Federation. The general population of persons with disabilities remained at 6,5 ± 0.11 cases per 10,000 of population of the appropriate age. The structure of general disability in severity was dominated by group III persons with disabilities, with a tendency to increase their specific weight and disability level. The proportion of persons with group I–II disabilities and their level tended to decrease