Relevance. Multiple sclerosis (MS) is a chronic progressive neurodegenerative autoimmune disease of the central nervous system, affecting mainly people of working age and leading to disability. Since this disease is a frequent cause of persistent disability, the importance and at the same time insufficiency of research in the field of regional specific programs related to disability due to MS is noted. Aims. To study the dynamics and features of the formation of primary and repeated disability due to MS among various age groups of the population, taking into account gender characteristics and severity of disability in Moscow in 2014–2021. Materials and methods. The study used examination materials of persons over 18 years of age with MS, collected in an electronic database of medical and social expertise (ITU) of the Federal State Institution "ITU Main Bureau for Moscow", acts, protocols of ITU, static f-088/06 on the re-examination of RS. Results. The last 8 years have been characterized by a decrease in general disability due to MS, with a decrease in the number of persons recognized as disabled for the first time (VPI) and an increase in the number of persons re-recognized as disabled (PPI). There is a drop in the proportion of disabled people of the first and second disability groups with an increase in the third group. In the structure of VPI and PPI due to MS, persons of working age prevailed with a slight decrease in the group of PPI. The gender structure was dominated by female persons. Conclusion. The study of indicators of disability due to MS among various population groups in modern conditions is of great importance for monitoring the level of disability of patients and maintaining a socially active life of the patient.

Более 20 лет проблема наркомании в Российской Федерации (РФ) носит острый социально-экономический, медицинский и правовой характер [1]. Период конца 90-х и начала 2000-х годов характеризуется широчайшим распространением героиновой наркомании, последствия ко

Introduction. In 2020, lung cancer (C34) ranked first in terms of causes of death from all malignant neoplasms and amounted to 1.8 million cases. Malignant neoplasms of the trachea, bronchi, lungs (C33, C34) occupy the first place in the structure of morbidity and mortality of men in the Russian Federation. Preventive measures should be directed to modifiable risk factors, which, in addition to smoking, include production factors. Thus, enterprises and organizations play an important role in the implementation of preventive measures. The study aims to consider the state of preventive measures aimed at preventing the development of malignant neoplasms of the trachea, bronchi, lungs (C33, C34) on the example of corporate practices of enterprises. Materials and methods. The researchers conducted a targeted literature search on the research topic, analyzed the materials of the library of the Russian Union of Industrialists and Entrepreneurs (RUIE). Results. Of the 80 programs presented on the RUIE website aimed at the company's employees and ensuring occupational safety and health at the workplace, only 12 contain measures aimed at preventing malignant neoplasms of the trachea, bronchi, lungs (C33, C34). These activities are mostly provided by anti-smoking programs. Conclusion. Concern is caused by the lack of prevention programs in the Library of Corporate Practices, the main purpose of which would be to prevent the development of malignant neoplasms of the trachea, bronchi, lungs (C33, C34) at enterprises of the oil and gas, metallurgical, mining, chemical industries.

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