The article is an attempt to explain the renewal of the articular cartilage in normalcy and osteoarthritis development by principles of mathematical modeling. Such models help to develop advanced methods of prevention, detection and treatment of osteoarthritis including molecular biotechnologies based on tissue engineering conception. We used histological images to perform structural analysis to discover the signs of active system and its states. Received data are useful to develop research protocols in cartilage tissue engineering.

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Four types of three dimensional plasma capillary porous titanium coatings for model intraosseous implants are developed. By means of pulsed microplasma oxidation in solutions or plasma spray ing of powders, additional bioactive coatings on the basis of calcium phosphates are deposited on the Ti coat ing surface. Shear strength values of the interface between the implants coated and osseous block after 16 weeks of implantation are 4.25-4.81 MPa, while for implants with additional plasma hydroxyapatite coat ing it exceeds 6.19 MPa after 4 weeks of implantation.

Abstract. The use of modern eco-oriented approaches in agriculture ensures not only the conservation of natural resources and the restoration of damaged ecosystems, but also the growth of agrocenoses productivity, increasing the tolerance of artificial ecosystems to unfavorable factors of natural and anthropic origin. The identification of consortia relations, carried out in the present article, allows to create the information database for accumulating and processing information on the patterns of ecosystem functioning in arid conditions. This provides researchers and farmers with a set of unified ecosystem tools to ensure sustainability and productivity of agrocenosis that increases the economic efficiency of management system and ensures the success of environmental management.The research carried out in three typical landscape localizations are intended to assess the state of agrocenoses, the nearby low-changed steppe sites and man-made intrusions, characterized by a high degree of anthropogenic load. The patterns of species distribution in the studied communities, the features of material and energy exchange will allow creating a database for describing the typical consortia, forecasting processes in agrocenoses and natural communities, controling the metabolism of the communities using metered-dose unidirectional biotic and abiotic agents. The distinctive natural and artificially modified communities are described. Soil and climate, phytocenological, zoological and microbiological characteristics of the studied objects are given. The peculiar forms of intrusions, the features of spatial distribution and quantitative dynamics of the species composing the communities are revealed and described; the typical species-edificators are pre-determined.The authors also determine the choice of consortium relations that are significant for the implementation of targeted high-precision management of biocenoses with the aim of increasing the stability of natural communities and the economic efficiency of agrocenoses.

Morphological changes in the ovaries and levels of sex hormones were studied in rats with chronic endotoxicosis. Long-term endogenous intoxication was associated with the development of sclerocystic ovary syndrome paralleled by hormone imbalance.