Objectives – to highlight the structure, function and localization of Alzheimer’s disease and to specify cognitive impairments related to it. Material and methods. The anatomic data of human brain structure were used. Results. The patterns of memory formation in the brain cortex are investigated. The brain cortex is presented as a type of syncytium consisting of elementary neural structures – cyclic neuronal circuits – memory elements. All cyclic neuronal circuits in a brain cortex are functionally interconnected. The connections between the neuronal circuits can be determined (imprinted) and stochastic (random). The intensity of stochastic communications defines the person's potential for creativity. The impairment of cyclic neuronal circuit connections results in either Alzheimer’s disease or in senile dementia of Alzheimer’s type. Conclusion. In case the cortex is considered as the syncytium, the memory storage element, it can be the reason of the human creativity. It is shown that the failure of the information transfer in the cortex syncytium or neurons destruction in the neuronal network results in Alzheimer’s disease or in senile dementia of Alzheimer’s type.

The problems connected to propagation of a gravitational field are considered. The law of electromagnetic radiation frequency change in gravitational field is shown. The problem of a gravitational field quantization is investigated. Energy of a graviton is found by two ways. First, on the basis of use quantum gravitational eikonal and Lagrangian of a gravitational field the energy of a solitary graviton is found. It is shown that graviton has the mass proportional to its frequency. Second, due to refusal from symmetric stresses tensor in structure of an energy-impulse tensor the quantum form of the energy-impulse tensor in Einstein's equation is found. It has allowed found the energy of a solitary graviton. Both ways of an energy graviton finding has given the identical result. It is shown that the solution of the Einsteins equation with use of the quantum form of an energy-impulse tensor for the certain direction represents the sum of a gravitational wave and a graviton. It is found out that at approach of a graviton to the massive bodies (double stars) radiating gravitational waves there is a resonant pumping of the gravitational field energy of these bodies to the gravitons with increase in their mass and frequency. It enables registration of the gravitons with the help of the detector located near to massive bodies. The assumption is made that dark energy of a gravitational field is all set of the graviton energies of a space.

Objectives -research of stochastic brain function in respect to creation of artificial intelligence. Material and methods. Mathematical modeling principles were used for simulation of brain functioning in a stochastic mode. Results. Two types of brain activity were considered: determinated type, usually modeled using the perceptron, and stochastic type. It is shown, that stochastic brain function modeling is the necessary condition for AI to become capable of creativity, generation of new knowledge. Mathematical modeling of a neural network of the cerebral cortex, consisting of the set of the cyclic neuronal circuits (memory units), was performed for the stochastic mode of brain functioning. Models of "two-dimensional" and "one-dimensional" brain were analyzed. The pattern of excitation in memory units was calculated in the "one-dimensional" brain model. Conclusion. Relying on the knowledge of the stochastic mode of brain function, a way of creation of AI can be offered. а-rhythm of a patient is a recommended focus of the therapist's attention in diagnostics and treatment of brain disorders. It was noted, that the alpha wave amplitude and frequency could indicate the cognitive, creative and intuitive abilities of a person.

Objective the analysis of a group of factors, leading to the increase of pulse pressure in the direction from aorta to microcirculation vessels, in order to define the diagnostic criterion for exception of primary arterial hypertension. Material and methods.In the study, the modelling of the functions of arteries in cardiovascular system was used. Results.The role of the increase of pulse pressure to the periphery of blood circulation was regarded as the diagnostic attribute of exception of the primary arterial hypertension. It was noted, that physical factors of the increase of pulse pressure to the periphery of blood circulation were insignificant. The cardiovascular reflex has the major influence on the increase of pulse pressure, its deterioration results in the decrease of this pressure. Conclusion.The analysis revealed the fact, that the normal ankle-brachial index allows for exclusion of primary arterial hypertension in a patient, even if the absolute values of arterial pressure are in the limits corresponding to this disease.