615.43The genus Polygonum L. (Polygonaceae) is represented in the flora of Siberia by 23 species that are used to treat inflammatory diseases of the kidneys and gastrointestinal tract. P. aviculare, the herb of which is used for diseases of the lymphatic system and kidney-stone illness and as a tonic and hemostatic agent, has been described in Tibetan medicine under the name "bri-ta-sa-dzin." The Tibetan name "nya-lo" corresponds to the species P. divaricatum and P. amphibium L. [1,2]. The herb and roots of these plants are used for inflammatory diseases of the stomach, intestines, gall bladder, uterus, and bladder [3]. The chemical composition of P. aviculare has been studied most. The phenolic compositions of P. divaricatum L. and P. angustifolium Pall. have been reported [4]. Phenolcarboxylic acids and flavonoids have been isolated from P. amphibium [5].Our goal was to study the phenolic composition of the aerial part of four Polygonum species (P. divaricatum, P. angustifolium, P. amphibium, and P. aviculare) by HPLC.The phenolic composition of the Polygonum plants was studied by HPLC for groups of compounds using isocratic elution. Three groups of compounds were examined, phenolcarboxylic and hydroxycinnamic acids (gallic, protocatechoic, chlorogenic, ferulic, caffeic, p-coumaric) (I), flavonoid glycosides (rutin, hyperoside, luteolin-7-glycoside, isoquercetin, avicularin, cosmosiin, kaempferol glycoside) (II), and flavonoid aglycons (luteolin, quercetin, apigenin, kaempferol) (III).