ель исследования. Тестирование (проверка) методики неинвазивного определения фракционного резерва кровотока (ФРК) на основании данных, полученных при проведении компьютерной томографической ангиографии (КТА) коронарных артерий. Результаты. Гидродинамический расчет кровотока в коронарной артерии позволил получить оценку ФРК с отклонением от инвазивно измеренных значений ФРК равным или меньшим 7%. Заключение. Продемонстрирован научный и клинический потенциал предложенной ранее методологии неинвазивного определения ФРК по результатам КТА для оценки функциональной значимости пограничных стенозов в коронарных артериях. Ключевые слова: фракционный резерв кровотока (ФРК), коронарные артерии, компьютерная томографическая ангиография (КТА), триангуляция поверхности, математическое моделирование.

This study is devoted to the accuracy of the optic navigation system “Neuroplan”. To assess the complex error of the system, a plastic model of the skull with 8 radiocontrast target points was developed. Twelve neurosurgeons with different levels of training participated in the study. The design of the study provided for each doctor performance of registration in the “Neuroplan” system at various positions of the model with subsequent hit at the target points. To select the optimal method of registration for different patient positions on the operating table, the registration table for anatomical landmarks (from 3 to 7) and on the surface was used. The analysis of the obtained results showed a high accuracy of the optic navigation system “Neuroplan”: in the side position of the scull model the target error averaged 1.57 [1.11; 2.13] mm, in the face down position – 1.69 [1.26; 2.19] mm, which is comparable with the declared accuracy of foreign analogues. When the experiment was repeated, it was shown that the system has high retest reliability.

In ischemic stroke, the condition of cerebral collateral circulation is one of the key factors determining the outcome. Digital subtraction angiography is considered the gold standard of evaluation of cerebral collateral circulation. However, computed tomography angiography is the most widely used method characterized by high level of conformity with subtraction angiography. Currently, several scales of visual evaluation of collateral circulation development in images obtained by computed tomography angiography are used. The scales describe the territory of stroke-associated cerebral artery, as well as details of various areas of the territory. The association between the score and severity of neurological deficit and volume of cerebral ischemia was demonstrated in numerous studies. However, consensus on the most reliable method of description of cerebral collateral status has not been reached. Use of modern methods of processing of medical images and artificial intelligence allowed to make a significant step towards automatization of collateral status evaluation with such benefits as high processing speed and resistance to subjective opinion. Despite low number of studies on this subject, implementation of automated solutions has already showed its effectiveness. In this review, scales for manual evaluation of cerebral collateral status are considered, their reliability is described, and current approaches to automated evaluation of collateral circulation in ischemic stroke are presented.

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