Relevance. At the end of 2019, an outbreak of a new coronavirus infection occurred in the People's Republic of China with an epicenter in Wuhan. On February 11, 2020, the World Health Organization assigned the infection its official name -COVID-19 («Coronavirus disease 2019»), and the International Committee on Taxonomy of Viruses on February 11, 2020 assigned the official name to the causative agent - SARS-CoV-2. The study is relevant due to the fact that the disease quickly spread around the planet with the active drift of the pathogen into the territory of the Russian Federation. As of 11/26/2020, worldwide 60 million 894 thousand people were infected with COVID-19, 1 million 430 thousand died, 42 million 90 thousand people recovered.Intention. Analysis of publications on the epidemiological spread of COVID-19 for the purpose of effective medical and psychological support during dynamic monitoring of the disease, and also for epidemiological well-being.Methodology. Scientific publications from domestic and foreign databases were analyzed.Results and Discussion. The global and rapid spread of COVID-19 disease has had a huge impact on all healthcare sectors around the world and has expanded the existing understanding of the nature of the course of this disease, and greatly facilitated the diagnosis, treatment and prevention of new coronavirus infection. The paper discusses the main issues of epidemiology, laboratory diagnostics and prevention of COVID-19, which are currently relevant. In the future, the massive use of vaccines against the new coronavirus will help create population immunity and protect the population from this disease, but today the issue has not yet been resolved, although it should be resolved in the near future.Conclusion. The issues of epidemiology and laboratory diagnostics of COVID-19 have not yet been finally resolved. The measures taken in Russia to prevent the import of HV are undoubtedly important and adequate to the current situation. At the same time, they cannot completely prevent cases of virus spreading (by those in the incubation period of COVID-19, or those with latent and hidden disease), which can lead to probable epidemiological problems in the future.

Additive technologies have been actively developing in recent decades. Their introduction into medicine provides new opportunities for reconstructive treatment, including animal patients.One of the most popular materials for 3D printing is titanium and titanium alloys. Their demand is explained by the properties of mechanical biocompatibility, strength and elasticity comparable to bone.The purpose of this review was to summarize data on the use of 3D printed titanium implants for the treatment of animals with bone defects. The search for information was carried out in the databases of scientific data of domestic and foreign literature and medical resources.The conducted studies have shown that the use of 3D printing technology makes it possible to design and create individual implants and endoprostheses based on images of each patient, exactly corresponding to the area of the defect. This approach reduces the time of surgical intervention, reduces the time of postoperative recovery.Possibility of obtaining the necessary specified porosity and surface roughness, which leads to a decrease in the micromovement of the boneimplant structure and promotes good osseointegration. These properties are the advantages of 3D printing implants made of titanium and titanium alloys.The given practical examples of the use of individual three-dimensional titanium implants show the possibilities of using additive technology for veterinary medicine.

In the last decade, the range of applications of three-dimensional printing (3D printing) in surgery has been expanding. In traumatology, orthopedics and rehabilitation of injuries of the upper limbs, there is growing interest in creating splints and orthoses that can take into account the individual anatomical features of the human body. Traditional orthoses and splints are not always convenient and can lead to undesirable consequences such as pain, swelling, pressure, or even lack of therapeutic effect. The prospects of 3D printing technology in medicine from the beginning of its mass introduction, the features of modeling, manufacturing and application of means for immobilization of injuries and diseases of the upper extremities according to domestic and foreign publications over the past 5 years are considered. The data on the functionality of 3D-printed tire structures and orthoses used to immobilize the upper limb are analyzed in comparison with traditional methods of fixation. Three-dimensional images of patients with injuries obtained using computed tomography, magnetic resonance imaging or using a 3D scanner can be used to create virtual 3D models of the forearm, wrist, fingers of the patient, and 3D printing with these anatomical models allows you to create personalized tires and orthoses. Thanks to an individual approach and the use of various solutions, three-dimensional printing can be widely used in traumatology and orthopedics. As a result of this approach, it becomes possible to implement and effectively use a variety of solutions that will find support in healthcare.

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