The article examines the case history with long-term follow-up tracing of the course and clinical picture of comorbid psychosexual and eating disorders in a patient with true transsexualism complicated by anorexia nervosa with dysmorphomania syndrome.

The article provides an analysis of the data on the causes of the development of such a widespread pathology as eating disorders. The influence of various factors on the formation of this severe and difficultly curable pathology is being investigated. The article provides an overview of the literary data of the historical works and proceedings of the Department of the Peoples’ Friendship University of Russia, which was at the forefront of the study of this pathology. English version of this article on pp. 321-329 is available at URL: https://panor.ru/articles/revisiting-the-relationship-between-sociocultural-and-biological-factors-in-the-development-of-eating-disorders-55-year-experience-of-the-department-of-psychiatry-and-medical-psychology-pfur/63933.html

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The article presents the analysis of correlation and dynamics of clinical and psychophysiological characteristics of the long-term effects of long-lasting abstinence from food on the example of 500 women with anorexia nervosa (AN), who applied for help to the Department of Psychiatry and Medical Psychology, FSAEI HE Peoples’ Friendship University of Russia in 1989-2017. The adverse effects of prolonged abstinence from food are shown; the indicators of catecholamine excretion (dopamine, adrenaline, norepinephrine), encephalography data, mental performance and memory of those examined at various stages of AN weight loss and gain were studied. The difference in the excretion of catecholamines in AN and psychogenic vomiting, which can be used for differential diagnosis, was demonstrated.