This article discusses the relationship between parameters of complete blood count (CBC) and cardiovascular diseases (CVD). The main advantages of CBC over other methods of CVD diagnostics are low cost and wide availability. At the same time, the low specificity of CBC is an important disadvantage, limiting its diagnostic value.After analyzing the results of numerous clinical studies, we concluded that the most important CBC are red cell distribution width, mean platelet volume, total leukocyte count, neutrophil to lymphocyte ratio, platelet-to-lymphocyte ratio, monocyte to high-density lipoprotein ratio. We discuss the diagnostic value of each of the above indicators in CVD. Careful attention to these parameters by clinicians can, to a certain extent, improve the therapeutic and diagnostic process in patients with CVD.
The concept of civic responsibility is poorly studied by modern political science and is not sufficiently used in the analysis of the Russian political situation. This article attempts to develop the concept of civic responsibility as a category in political science using political, sociological and institutional approaches. The scientific novelty lies in the deployment of the concept of civic responsibility in the institutional context of civil society and the state. The identification of the normative and value structure of civic responsibility and its congruence in the institutional environment and the assessment of the development potential of civic responsibility will allow the better understanding of Russian politics and Russian society, as well as the expansion of the possibilities for influencing the process of the formation of civic responsibility as a stable foundation of modern politics. For empirical verification of theoretical assumptions, we used the data of an all-Russian representative survey of the population aged 18 years and older conducted by the comparative political research department of the Institute of Sociology of the Federal Center of Theoretical and Applied Sociology of the Russian Academy of Sciences (with the support of the Center of Social Forecasting and Marketing) in June 2019. The size of the sampled population was 700 people (OSPI-2019).
Aim. To compare the PESI and GRACE scores in assessing the risk of hospital outcomes in patients with pulmonary embolism.Material and methods. The study included 383 patients with pulmonary embolism (PE), hospitalized during the period of April 4, 2003 on September 18, 2014; 190 (49,6%) are men, the average age is 57,4 years±14,4 years. We considered the patient’s anamnesis, complaints, results of biochemical and instrumental tests, as well as the treatment carried out to the patients.Results. According to the risk stratification of PESI score, 86 (22,5%) patients had a very low risk of death, 88 (22,9%) had a low risk, 94 (24,5%) had an intermediate risk, 60 (15,%) — high risk and 55 (14,4%) patients have a very high risk. The combination of three ECG signs (SI-QIII, right bundle branch block and T-wave inversion in V1-V3) was significantly more common in patients with a very high PE risk — 14,5% (p=0,025). The most reliable sign of the most echographic (echoCG) criteria was dilatation of right ventricle (RV) (p=0,009) in a group of patients with a very high PE risk. According to the GRACE scale, 112 (29,2%) patients were assigned to the low risk group, and 271 (70,8%) patients — to the high risk group. ECG signs were observed more frequently in the high risk group: SI-QIII, T-wave inversion in III, V1-V3 leads, right bundle branch block (p<0,05). Pulmonary hypertension and RV dilatation according to echoCG prevailed in the high risk group (98,4% and 85,1%, respectively), p<0,05. The minimum value of points on the GRACE score for the deceased patients was 118 points. The GRACE scale showed high predictive ability with a sensitivity of 96% and a specificity of 63% (AUC=0,811, CI 95% 0,0738-0,884). However, the PESI score had a slightly greater predictive value with a sensitivity of 100% and a specificity of 53% (AUC=0,879 compared with AUC=0,811 for the GRACE scale). Analysis of the PESI and GRACE scores showed a moderate correlation between them (r=0,668).Conclusion. The GRACE score showed a high predictive value for adverse outcomes in PE patients with a sensitivity of 96% and a specificity of 63%. The minimum score on the GRACE score for deceased patients was 118 points.
Цель: определение технических характеристик при выборе медицинских просмотровых мониторов, влияющих на качество просматриваемого изображения. Материалы и методы. Анализ действующих нормативных документов, отечественной и мировой научной литературы, регламентирующих параметров для медицинских просмотровых мониторов. Результаты и их обсуждение. В российской и зарубежной литературе встречаются единичные публикации, посвященные оценке и анализу медицинских мониторов, а нормативные документы отсутствуют. По данным технической документации представленных в России медицинских просмотровых мониторов были сформированы основные требования, предъявляемые к медицинским просмотровым мониторам, используемые при работе на современных цифровых маммографических системах. В статье проанализированы основные параметры мониторов, влияющие на качество визуализируемого изображения, выделены основные параметры цифровых детекторов, установленных на маммографах, и даны рекомендации для выбора медицинского монитора, отвечающего параметрам маммографа. Выделены основные параметры для мониторов, такие как разрешающая способность, соотношение яркости и контрастности, время отклика, которые при правильном соотношении в значительной степени повышают качество работы врача-рентгенолога. Заключение. Медицинские просмотровые мониторы должны отвечать физико-техническим параметрам установленного маммографа; для повышения качества работы врачей-рентгенологов, занимающихся диагностикой молочных желез в рамках одного ЛПУ целесообразно выбирать медицинские просмотровые мониторы одной фирмы-производителя; техническое обслуживание медицинских просмотровых мониторов следует осуществлять не реже двух раз в год. Ключевые слова: медицинские мониторы высокого разрешения, цифровая маммографическая система, молочная железа.
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