The literature data on the effect of smoking on the development of placental lesions and complications of pregnancy are analyzed. The adverse effect of smoking on the morphofunctional state of the placenta is based on toxic substances that are released during smoking. Disturbances in the development of the placenta are noted both with active smoking and with passive smoking, both with smoking before pregnancy and during it. Smoking and tobacco smoke contribute to the more frequent development of miscarriage, chorioamnionitis, impaired of vascularization of chorion villi, previa and placental abruption, premature rupture of the membranes. Therefore, it is necessary to state the fact of smoking a pregnant woman in a clinical diagnosis. At the same time, smoking refers to preventable risk factors for complications of pregnancy and fetus.

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