The aims of this research were to: (1) provide a theoretical basis for in鄄depth analysis of the influence of human activities on estuarine wetlands over a regional scale; (2) quantify the impact of anthropogenic interference on the landscape pattern index; and (3) establish a theoretical basis for the monitoring and evaluation of anthropogenic interference in estuarine wetlands. Based on aerial photographs from 1958, 1970, and 1984 (2 m resolution) , and the spot5 image of 2008 (5 m resolution) , this study explored the spatiotemporal dynamics of hemeroby and the landscape pattern response scheme through hemeroby analysis, landscape pattern analysis, spatial patch analysis, and GIS spatial analysis in the Dayang estuary. The research evaluates: 1) the primary forcing landscape factors for spatial and temporal variation of hemeroby in an estuarine wetland; 2) the response mechanism of landscape pattern index on the type of hemeroby; and 3) landscape indices associated with hemeroby in space. Results indicate that: 1) completely hemeroby regions increased from 4. 16 km 2 in 1958 to 9. 16 km 2 in 2008, while partially hemeroby regions increased from 115. 82 km 2

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