A carbohydrate fraction, AIP1 from Artemisia iwayomogi suppresses pulmonary eosinophilia and Th2-type cytokine production in an ovalbumin-induced allergic asthma. Down-regulation of TNF-α expression in the lung

FICZ, a Tryptophan photoproduct, suppresses pulmonary eosinophilia and Th2-type cytokine production in a mouse model of ovalbumin-induced allergic asthma

“…Sensitization and challenge with OVA was previously described [32]. On day 0, mice were sensitized with an intraperitoneal (i.p.)…”

Chlorogenic acid suppresses pulmonary eosinophilia, IgE production, and Th2-type cytokine production in an ovalbumin-induced allergic asthma: Activation of STAT-6 and JNK is inhibited by chlorogenic acid

“…Sensitization and challenge with OVA was previously described [19]. On day 0, mice were sensitized with an intraperitoneal (i.p.)…”

“…We previously reported that in an ovalbumin-induced allergic asthma model in mice, AIP1, a water-soluble carbohydrate fraction from Artemisia iwayomogi, suppressed pulmonary eosinophilia and Th2 cytokine expression in the lungs as well as serum IgE levels [19]. Flow cytometric analysis of lung-infiltrating cells showed that the surface levels of CD11c and MHC II in CD11c+MHC II+ cells, potent dendritic cells, decreased in animals treated with AIP1.…”

A Carbohydrate Fraction, AIP1, fromArtemisia IwayomogiReduces the Action Potential Duration by Activation of Rapidly Activating Delayed Rectifier K+Channels in Rabbit Ventricular Myocytes

“…AIP1 also reduced allergic asthma via the down-regulation of tumor necrosis factor-alpha (TNF-α) expression [21]. AIP1 may also act as a potent anti-oxidant.…”