Introduction: Typhoid fever is an acute, generalized infection of the
reticuloendothelial system, which is caused by Salmonella typhi and
causes substantial and hepatic complications and biochemical changes.
Currently, the diagnostic test is isolation of bacteria from blood,
stool and occasionally urine, but serologic tests are still commonly
used, and there is still a necessity for the rapid and reliable
diagnostic test for typhoid fever. The objective of this study was to
determine the hematological changes in adult typhoid patients as
compared to healthy control. Methodology: A total of 50 patients and 50
healthy individuals were enrolled in this research, and variations in
hematological factors were studied. Results: Hematological parameters
were found deranged in typhoid fever including hemoglobin (low,
10.97±0.88), hematocrit (low, 37.72±1.40), ESR (high 45.08±13.42),
platelet count (high 588840±97185), WBCs count (high 38267±22279),
neutrophil percentage (high, 73.56±9.96), lymphocyte percentage (low,
21.24±10.08), and NLCR (high, 5.14±4.00) as compared to healthy control
group. Conclusion: This differentiating pattern is easy to obtain by
minimal invasive procedure and can be used for typhoid infection
diagnosis.