“…Hence, the large computational effort required, in addition to the uncertainty involved in the estimation process, represents an obstacle against the statistical design centering approaches and needs some innovative treatments for such problems. The second approach is classified as a geometric approach [9,13,14,19,[35][36][37][38][39][40][41]. It treats the problem implicitly by finding the center of a body approximating the feasible region, with the assumption that the feasible region is bounded and convex.…”