A Rare Case of Takotsubo Syndrome and Acute Coronary Syndrome of the Right Coronary Artery

Mencer, Nicholas; Justice, Larry; Black, William C.; Litton, Kayleigh M.

doi:10.1155/2019/9128273

Cited by 4 publications

(4 citation statements)

References 21 publications

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“…The third and rarest condition that may occur is acute coronary syndrome as a consequence of TTS [78]. As discussed later, this reciprocal cause-and-effect relationship between CAD and TTS is still under discussion.…”

Section: Coexistence Of Takotsubo and Coronary Artery Disease-coincid...mentioning

confidence: 99%

“…Lin and Young showed that the occurrence of cyclic blood flow decreases in the canine coronary arteries grew by 60% when the plasma epinephrine concentration was raised to about 27 nmol/L [91]. Given that catecholamines are known to have prothrombotic effects and that TTS is linked to an increase in catecholamines, it is plausible that TTS preceded ACS in certain case reports that have been documented in the literature [78]. Despite coronary artery thrombosis, SCAD, or LV systolic dysfunction as potential pathological mechanisms, ACS in this setting might sometimes be secondary to embolic events from a LV thrombus developed in the akinetic LV apex.…”

Section: Takotsubo Triggered By Ischemia-the Chicken-egg Paradoxmentioning

confidence: 99%

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Takotsubo Syndrome and Coronary Artery Disease: Which Came First—The Chicken or the Egg?

Celeski,

Nusca,

De Luca

et al. 2024

JCDD

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Takotsubo syndrome (TTS) is a clinical condition characterized by temporary regional wall motion anomalies and dysfunction that extend beyond a single epicardial vascular distribution. Various pathophysiological mechanisms, including inflammation, microvascular dysfunction, direct catecholamine toxicity, metabolic changes, sympathetic overdrive-mediated multi-vessel epicardial spasms, and transitory ischemia may cause the observed reversible myocardial stunning. Despite the fact that TTS usually has an acute coronary syndrome-like pattern of presentation, the absence of culprit atherosclerotic coronary artery disease is often reported at coronary angiography. However, the idea that coronary artery disease (CAD) and TTS conditions are mutually exclusive has been cast into doubt by numerous recent studies suggesting that CAD may coexist in many TTS patients, with significant clinical and prognostic repercussions. Whether the relationship between CAD and TTS is a mere coincidence or a bidirectional cause-and-effect is still up for debate, and misdiagnosis of the two disorders could lead to improper patient treatment with unfavourable outcomes. Therefore, this review seeks to provide a profound understanding of the relationship between CAD and TTS by analyzing potential common underlying pathways, addressing challenges in differential diagnosis, and discussing medical and procedural techniques to treat these conditions appropriately.

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Section: Coexistence Of Takotsubo and Coronary Artery Disease-coincid...mentioning

confidence: 99%

Section: Takotsubo Triggered By Ischemia-the Chicken-egg Paradoxmentioning

confidence: 99%

Takotsubo Syndrome and Coronary Artery Disease: Which Came First—The Chicken or the Egg?

Celeski,

Nusca,

De Luca

et al. 2024

JCDD

View full text Add to dashboard Cite

show abstract

“…Clinically, it mimics an acute coronary syndrome (ACS), but coronaries are normal on cardiac catheterization. It is likely caused by excessive catecholamine stimulation although the exact etiology is still under discussion [ 3 , 5 , 6 ]. In the intraoperative setting, it can be triggered by the surgical condition, the surgical procedure, or the anesthesia itself [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

Cardiac Arrest During Spinal Surgery: A Multidisciplinary Approach and Management of Takotsubo Syndrome

Silva¹,

Carrillo-Alfonso²,

Amorim³

2022

Cureus

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Cardiac arrest (CA) in the operating room is rare. Among known perioperative CA causes, Takotsubo syndrome (TTS) is a well-recognized one. Perioperative TTS is more common than existing reported cases therefore anesthesiologists should be aware of its diagnosis and management. TTS is an acquired and selflimited stress cardiomyopathy usually triggered by a precipitating stress factor and should be considered in any hospitalized patient presenting with symptoms such as acute coronary syndrome, cardiac arrhythmias or CA. A 67-year-old woman presented for lumbar discectomy in knee-chest position suffered CA two hours after the beginning of surgery. After a thorough examination, TTS was determined as the cause. This case report highlights the importance of TTS as a differential diagnosis of CA in the intraoperative setting as well as the usefulness of multimodal monitoring with cerebral monitoring to assist the prompt pulseless electric activity diagnosis. To our knowledge, this is the first case report in such circumstances.

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“…Stress factors related to Takotsubo cardiomyopathy6,10,11,[24][25][26][27][28][29][30][31][32][33][34][35][36][37][38][39][40][41][42][43] …”

mentioning

confidence: 99%

Cardiomiopatia de Takotsubo da patogênese ao diagnóstico: estado da arte

Brito¹,

Castro²,

Zambianco³

et al. 2020

Rev. Med. (São Paulo)

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A cardiomiopatia de Takotsubo (CMT) apresenta-se, normalmente, por hipocinesia, discinesia ou acinesia transitória do ápice do ventrículo esquerdo, com duração de até quatro semanas, desencadeada por estresse físico ou emocional. Com maior incidência entre mulheres pós-menopausa, consiste em uma síndrome clínica confundida com infarto agudo do miocárdio (IAM), devido aos achados clínicos e laboratoriais em comum. A cada 100 diagnósticos feitos de síndrome coronariana aguda, cerca de 2 tratam-se da CMT. Apesar de ter sido descrita em 1990 e exigir terapêutica distinta, ainda não há consenso internacional no que se refere aos critérios diagnósticos. Este artigo busca revisar as publicações dos últimos 30 anos sobre o tema em relação a epidemiologia, patogênese, manifestações clínicas, achados laboratoriais, critérios e métodos diagnósticos, enumerando medidas que permitam diferenciar IAM de CMT na prática clínica.

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A Rare Case of Takotsubo Syndrome and Acute Coronary Syndrome of the Right Coronary Artery

Cited by 4 publications

References 21 publications

Takotsubo Syndrome and Coronary Artery Disease: Which Came First—The Chicken or the Egg?

Takotsubo Syndrome and Coronary Artery Disease: Which Came First—The Chicken or the Egg?

Cardiac Arrest During Spinal Surgery: A Multidisciplinary Approach and Management of Takotsubo Syndrome

Cardiomiopatia de Takotsubo da patogênese ao diagnóstico: estado da arte

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