In this paper, considering a class of skid-to-turn (STT) missile with impact angle constraint to intercept the maneuvering target, a three-dimensional integrated guidance and control law based on the fractional integral terminal sliding mode control (FITSMC) scheme is proposed. Firstly, a three-dimensional integrated guidance and control model is established for missile-target relative motion and nonlinear missile dynamics with multiple system uncertainties and unknown disturbances. Secondly, in order to achieve the desired impact angle in finite-time without singularity, a novel nonsingular FITSMC scheme is employed to construct the sliding surface, and a modified filter is applied to dynamic surface control design. Also, an extended state observer is introduced to estimate and compensate the system uncertainties and unknown disturbances. Then, a robust integrated guidance and control scheme with impact angle constraint is developed using aforementioned techniques. Furthermore, the finite-time stability of the closed-loop system is proven based on Lyapunov theory. Finally, the effectiveness and robustness of the proposed integrated guidance and control algorithm are verified through numerical simulations.INDEX TERMS Integrated guidance and control, impact angle constraint, fractional integral terminal sliding mode control, finite-time convergence, dynamic surface control.