Activities of different types of Thai honey on pathogenic bacteria causing skin diseases, tyrosinase enzyme and generating free radicals

Abstract

BackgroundHoney is a natural product obtained from the nectar that is collected from flowers by bees. It has several properties, including those of being food and supplementary diet, and it can be used in cosmetic products. Honey imparts pharmaceutical properties since it has antibacterial and antioxidant activities. The antibacterial and antioxidant activities of Thai honey were investigated in this study.ResultsThe honey from longan flower (source No. 1) gave the highest activity on MRSA when compared to the other types of honey, with a minimum inhibitory concentration of 12.5% (v/v) and minimum bactericidal concentration of 25% (v/v).Moreover, it was found that MRSA isolate 49 and S. aureus were completely inhibited by the 50% (v/v) longan honey (source No. 1) at 8 and 20 hours of treatment, respectively. Furthermore, it was observed that the honey from coffee pollen (source No. 4) showed the highest phenolic and flavonoid compounds by 734.76 mg gallic/kg of honey and 178.31 mg quercetin/kg of honey, respectively. The antioxidant activity of the honey obtained from coffee pollen was also found to be the highest, when investigated using FRAP and DPPH assay, with 1781.77 mg FeSO4•7H2O/kg of honey and 86.20 mg gallic/kg of honey, respectively. Additionally, inhibition of tyrosinase enzyme was found that honey from coffee flower showed highest inhibition by 63.46%.ConclusionsHoney demonstrates tremendous potential as a useful source that provides anti-free radicals, anti-tyrosinase and anti-bacterial activity against pathogenic bacteria causing skin diseases.

Predictive mathematical modeling for EC50 calculation of antioxidant activity and antibacterial ability of Thai bee products

“…On the other hand, the TPC of Chinese propolis showed slightly higher values as ranged from 262 to 299 mg GAE/g . Meanwhile, the TPC of our bee pollen extracts (24.22 mg GAE/g) was in agreement with those of bee pollen reported from Portugal (25.3-28.8 mg GAE/g) and Spain (18.6-32.2 mg GAE/g) (Pascoal et al, 2014).The TPC of our honey (0.57 mg GAE/g)was comparable to honey collected in Thailand (0.23-0.73 mg GAE/g) by Jantakee and Tragoolpua (2015) and in Portugal (0.23-0.73 mg GAE/g) by Ferreira et al (2009). However, this value was lower when compared to honey from Brazil (1.05 mg GAE/g) (Sant'ana et al, 2014).The variation of TPC from the bee products from various origins could be attributed to climate and environmental factors such as humidity, temperature and soil composition.…”

Biomedical Activity and Related Volatile Compounds of Thai Honeys from 3 Different Honeybee Species

“…This highest value was significantly higher than that of the well‐known manuka honey of New Zealand. The amount of phenolics in our honey samples was higher than the phenolic content of honey samples studied by Jantakee and Tragoolpua () (234.66 to 831.88 mgGAE/kg) and Limpawattana () (58.7 to 165.2 mgGAE/100 g) though theirs were also Thai honeys. Moreover, the antioxidant potential and amount of phenolics in unprocessed coffee honey were higher than those in rambutan honey (5.8 mg/mL and 1160.39 mgGAE/kg, respectively) which is reported to have the highest antioxidant and phenolic content among Thai honeys in a previous study (Srisayam and Chantawannakul ).…”

“…Gram‐positive bacteria ( B. cereus , M. luteus , S. aureus , and S. epidermidis ) were more susceptible to growth inhibition by honeys than Gram‐negative bacteria ( E. coli , K. pneumoniae , P. mirabilis , P. aeruginosa , S. typhimurium , and S. marcescens ). Jantakee and Tragoolpua () investigated the antibacterial activity of Thai honeys against Gram‐positive bacteria using the broth dilution method. Their MIC values (of longan honey, wild honey, lychee honey, and coffee honey) were higher than our results (5% to 17% in average) with a range of 25% to 50% in average.…”

Propiedades fisicoquímicas de mieles monoflorales de encenillo de la zona altoandina en Boyacá, Colombia

“…3,[9][10][11][12][13] Este producto natural, es ampliamente usado en la industria alimentaria, cosmética y farmacéutica. [14][15][16] Los atributos de color, aroma, textura y sabor de los alimentos son propiedades deseables que marcan la tendencia de los consumidores. Como cualquier producto alimenticio, las mieles poseen propiedades organolépticas que las hacen diferenciables a causa de sus componentes aromáticos dominantes según sea el origen botánico del néctar.…”