Adipose tissue content and distribution in children and adolescents with bronchial asthma

Umławska, Wioleta

doi:10.1016/j.rmed.2014.11.006

Cited by 15 publications

(15 citation statements)

References 32 publications

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“…One is medication use, including corticosteroids and antidepressant medications. Some studies showed that long-term treatment with corticosteroids, even in inhaled forms [48], can influence lipid metabolism by increasing the uptake of lipids from the digestive system and enhancing lipids' storage in tissues, especially in the trunk [49]. Additionally, depressive symptoms were common and associated with asthma activity in children [50], and the use of some antidepressant medications can also lead to weight gain and be responsible for some proportion of the excess obesity [51].…”

Section: Discussionmentioning

confidence: 99%

Association between Physician-Diagnosed Asthma and Weight Status among Chinese Children: The Roles of Lifestyle Factors

Lai

Zhang

Zeng

et al. 2020

IJERPH

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Childhood asthma and obesity have posed a parallel epidemic over the past few decades. However, whether asthma diagnosis is associated with obesity, and what the roles of lifestyle factors play in this relationship, remained unclarified. This study aimed to investigate the association between asthma and weight status in Chinese children and explore the potential mediating and/or modifying roles of lifestyle factors in the association. In this cross-sectional study, 16,837 children aged 6–12 years were recruited from Guangzhou, China. Participants’ information on physician-diagnosed asthma was collected from parents, and data on physical activity, screen time, and sleeping were reported in a validated questionnaire. Height and weight were objectively measured, and weight status was classified by body mass index (BMI). Multiple logistic regression analysis and mediation analysis were used. Results showed that asthmatic children were at significantly higher risk of obesity (odds ratio (OR) 1.51, 95% confidence interval (CI) 1.03, 2.21) compared with non-asthmatic children. More importantly, this increased risk was even greater in children with moderate-to-vigorous physical activity <60 min/d and children with screen time >2 h/d (both Pinteraction < 0.05). Also, a positive relationship of asthma with overweight was found in children with screen time >2 h/d (OR 3.92, 95% CI 1.56, 9.88), while a negative association was observed between asthma and underweight in children aged 9–12 years (OR 0.23, 95% CI 0.06, 0.92). Mediation analysis indicated that these associations were not mediated by physical activity, screen time, or sleeping. The findings suggested that physician-diagnosed asthma was associated with higher risks of overweight and obesity, and these risks might be exacerbated by insufficient physical activity and prolonged screen time.

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Section: Discussionmentioning

confidence: 99%

Association between Physician-Diagnosed Asthma and Weight Status among Chinese Children: The Roles of Lifestyle Factors

Lai

Zhang

Zeng

et al. 2020

IJERPH

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“…The biological mechanisms underlying the increased risk of obesity due to asthma are uncertain. Some studies showed that long-term treatment with glucocorticosteroids in children with asthma children can influence lipid metabolism by increasing the uptake of lipids from the digestive system and enhancing lipids storage in tissues, especially in the trunk (25). However, results of the association between asthma medication treatment and increased risk of obesity have not been consistent (26).…”

Section: Discussionmentioning

confidence: 99%

Effects of Childhood Asthma on the Development of Obesity among School-aged Children

Chen

Salam

Alderete

et al. 2017

Am J Respir Crit Care Med

117

104

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Rationale: Asthma and obesity often occur together in children. It is unknown whether asthma contributes to the childhood obesity epidemic.Objectives: We aimed to investigate the effects of asthma and asthma medication use on the development of childhood obesity.Methods: The primary analysis was conducted among 2,171 nonobese children who were 5-8 years of age at study enrollment in the Southern California Children's Health Study (CHS) and were followed for up to 10 years. A replication analysis was performed in an independent sample of 2,684 CHS children followed from a mean age of 9.7 to 17.8 years.Measurements and Main Results: Height and weight were measured annually to classify children into normal, overweight, and obese categories. Asthma status was ascertained by parent-or self-reported physician-diagnosed asthma.Cox proportional hazards models were fitted to assess associations of asthma history with obesity incidence during follow-up. We found that children with a diagnosis of asthma at cohort entry were at 51% increased risk of developing obesity during childhood and adolescence compared with children without asthma at baseline (hazard ratio, 1.51; 95% confidence interval, 1.08-2.10) after adjusting for confounders. Use of asthma rescue medications at cohort entry reduced the risk of developing obesity (hazard ratio, 0.57; 95% confidence interval, 0.33-0.96). In addition, the significant association between a history of asthma and an increased risk of developing obesity was replicated in an independent CHS sample.Conclusions: Children with asthma may be at higher risk of obesity. Asthma rescue medication use appeared to reduce obesity risk independent of physical activity.

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“…Qualitative signs of digital dermatoglyphics as markers of diseases of atopic nature 13.75% for high school students and 12.17% for secondary school students [16]. It is noted that individuals of different sex, age and type of body structure are very strikingly affected by these diseases [6,23,25,26,28,29].…”

Section: Issn1861-031x Eissn 2616-6208mentioning

confidence: 99%

Qualitative signs of digital dermatoglyphics as markers of diseases of atopic nature

Cherkasov

Maievskyi

Serheta

et al. 2019

Biomed. and Biosoc. Anthrop.

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The lawfulness of the application of the method of dermatoglyphics in the study of atopic diseases is ensured by the polygenic inheritance of signs of dermatoglyphics, on the one hand, and the pathogenetic heterogeneity of these diseases, on the other hand, as well as high informative ability of signs of dermatoglyphics as markers of diseases of hereditary and multifactorial nature. The purpose of the study is to detect differences in qualitative signs of digital dermatoglyphics between patients with atopic dermatitis, allergic rhinitis and bronchial asthma. Primary indicators of digital dermatoglyphics of sick young men and young women of the Podillia region are taken from the data bank of the research center of the National Pirogov Memorial Medical University, Vinnytsya and were used in previous studies when compared with the practically healthy population of this region. Imprints were obtained by the method of “printing ink” by Gladkova T. D. By the method of Cummins H. and Midlo Ch. a dermatological study was performed for 320 young men and young women with allergic rhinitis (n=69), bronchial asthma (n=108) and atopic dermatitis (n=143). The frequency and location of 8 types of finger patterns were subject to analysis. Statistical processing of the obtained results was carried out in the package “Statistica 6.1” using nonparametric methods. The reliability of the difference in values between independent qualitative values was determined by the formula of Weber E. (1961). The specificity of the digital typology of atopic diseases is established, which is based on the differences in the frequency and location of the whorl, central pocket and arches between the young men, except those indicated - a random pattern between young women, patients with atopic dermatitis, bronchial asthma, allergic rhinitis. Additionally, when comparing young men, patients with allergic rhinitis with patients with bronchial asthma and atopic dermatitis - ulnar loop; for bronchial asthma with patients with allergic rhinitis and atopic dermatitis - lateral pocket loop (in young men) and ulnar, lateral pocket and double loops (in young women); when comparing young men, patients with atopic dermatitis with patients with bronchial asthma, and allergic rhinitis - a random pattern.

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Adipose tissue content and distribution in children and adolescents with bronchial asthma

Cited by 15 publications

References 32 publications

Association between Physician-Diagnosed Asthma and Weight Status among Chinese Children: The Roles of Lifestyle Factors

Association between Physician-Diagnosed Asthma and Weight Status among Chinese Children: The Roles of Lifestyle Factors

Effects of Childhood Asthma on the Development of Obesity among School-aged Children

Qualitative signs of digital dermatoglyphics as markers of diseases of atopic nature

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