Administration of Metoclopramide for Prevention of Nausea and Vomiting during Epidural Anesthesia for Elective Cesarean Section

Chestnut, D.H.; Vandewalker, G. E.; Owen, Cindy L.; Bates, James N.; Choi, W. W.

doi:10.1097/00000542-198704000-00022

Cited by 55 publications

(5 citation statements)

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“…The incidence of nausea and vomiting during and after regional anaesthesia for caesarean section is relatively high when no prophylactic antiemetic is provided (1,2). The incidence of emetic episodes in this study was as high as 60% in patients who had received placebo, and was in agreement with previous studies (1-3).…”

Section: Discussionsupporting

confidence: 92%

“…The doses of other antiemetics, droperidol and metoclopramide, were chosen from the results of several investigations for the prevention of nausea and vomiting in parturients undergoing caesarean section under regional anaesthesia (1,2,7). More conventional doses of these antiemetics, droperidol 1.25 mg and metoclopramide 10 mg, have been used to prevent emetic symptoms because these two drugs are not associated with adverse effects which include excessive sedation and extrapyramidal signs (4).…”

Section: Discussionmentioning

confidence: 99%

“…0 Acta Anaesthesiologica Scandinauica 42 (1 998) AUSEA and vomiting occur frequently during and N after caesarean section under regional anaesthesia when no prophylactic antiemetic is provided (1,2). We have recently demonstrated that granisetron, a selective 5-hydroxytryptamine type 3 (5-HT3) receptor antagonist, is effective for the prevention of emetic symptoms during spinal anaesthesia for caesarean section (3).…”

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confidence: 99%

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Prevention of nausea and vomiting with granisetron, droperidol and metoclopramide during and after spinal anaesthesia for caesarean section: A randomized, double‐blind, placebo‐controlled trial

Fujii

Tanaka

Toyooka

1998

Acta Anaesthesiol Scand

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Section: Discussionsupporting

confidence: 92%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

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Prevention of nausea and vomiting with granisetron, droperidol and metoclopramide during and after spinal anaesthesia for caesarean section: A randomized, double‐blind, placebo‐controlled trial

Fujii

Tanaka

Toyooka

1998

Acta Anaesthesiol Scand

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“…(4) The aetiology of emetic symptoms in parturiant is multifactorial and complex. The increased progesterone level during pregnancy decreases gastrointestinal motility and reduces lower oesophageal pressure.…”

Section: Discussionmentioning

confidence: 99%

Comparision Be T Ween Metoclopramide and Ondansetron for Prevention of Nausea and Vomiting in Caesarean Delivery Under Spinal Anaesthesia

K¹,

Heisnam²,

Lobo³

et al. 2015

jemds

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AIM OF STUDY:To evaluate the anti-emetic efficacy of bolus doses of metoclopramide and ondansetron in preventing nausea and vomiting in caesarean section under spinal anaesthesia. METHODS: Sixty patients of ASA-Ī and ĪĪ undergoing elective caesarean section were randomly divided into 2 groups of 30 each. Group A (n=30) received IV metoclopramide 10mg and Group B (n=30) received IV ondansetron 4mg, 30 minutes prior to spinal anaesthesia. Anaesthetic management was standardized and incidence of nausea, retching and vomiting was compared between the two groups. RESULTS: The maternal characteristics regarding age, weight and gestational period were not significantly different between the two groups. There was also no statistically significant (p>0.05) difference of anti-emetic effects (Nausea, vomiting) between the two studied drugs. CONCLUSION: No single intervention is available to completely eliminate nausea and vomiting. Metoclopramide is as effective as ondansetron in preventing the incidence of nausea and vomiting in caesarean delivery under spinal anaesthesia.

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“…Carvalho reported the incidence of intraoperative nausea and vomiting to be more than 66% [1]. Santos and Lussos reported the incidence of nausea and vomiting during caesarean section performed under spinal anaesthesia to be 50% to 80% when no prophylactic antiemetic was given [2,3]. Woman having cesarean delivery delivery, when compared with other surgical procedures, often receive neuraxially administered opioids for post-operative pain relief, which may increase the incidence of nausea and vomiting [4].…”

Section: Introductionmentioning

confidence: 99%

Study of propofol for control of nausea and vomiting during caesarian delivery under spinal anaesthesia

Ray¹,

Das

Patel

et al. 2022

ijhs

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Introduction: The incidence of nausea-vomiting during and immediately after caesarean delivery with spinal anesthesia is common occurrence and annoying problems to all concerned. The abrupt diaphragmatic contractions, present in emesis are uncomfortable to the patient and may cause protrusion of the abdominal viscera, rendering surgery more difficult and increasing the risk of visceral injuries. If the stomach is full, aspiration is an additional hazard. Therefore, it seems to be advisable to prevent it during spinal anesthesia for caesarean section. Aim & Objective: To assess the magnitude of intraoperative and post operative nausea, retching and vomiting in parturients, Evaluate the efficacy of propofol at subhypnotic doses for reducing emetic episodes in parturients. Observation: The result of study indicates the incidence of intraoperative emetic episodes in caesarean delivery is very high. In the study 6% of patients in propofol group experienced intra-operative vomiting, while in placebo group it was 30%(p=0.004). Conclusion: Propofol at 1mg/kg/hr infusion, administered immediately after clamping the umbilical cord, significantly decreased the incidence and severity of nausea, retching and vomiting and the need for rescue antiemetic therapy compared with placebo.

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Administration of Metoclopramide for Prevention of Nausea and Vomiting during Epidural Anesthesia for Elective Cesarean Section

Cited by 55 publications

References 0 publications

Prevention of nausea and vomiting with granisetron, droperidol and metoclopramide during and after spinal anaesthesia for caesarean section: A randomized, double‐blind, placebo‐controlled trial

Prevention of nausea and vomiting with granisetron, droperidol and metoclopramide during and after spinal anaesthesia for caesarean section: A randomized, double‐blind, placebo‐controlled trial

Comparision Be T Ween Metoclopramide and Ondansetron for Prevention of Nausea and Vomiting in Caesarean Delivery Under Spinal Anaesthesia

Study of propofol for control of nausea and vomiting during caesarian delivery under spinal anaesthesia

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