Aktivitas Antibakteri Ekstrak Bunga Telang (Clitoria ternatea L.) terhadap Bakteri Patogen

Abstract

<p>Penyakit manusia dapat disebabkan oleh kontribusi bakteri yang menyebabkan infeksi. Penggunaan tanaman sebagai pengobatan tradisional memainkan peran penting dalam kesehatan karena dianggap sebagai salah satu sumber yang paling menjanjikan untuk penemuan agen antimikroba baru yang minim efek samping. Bunga telang mulai dilirik masyarakat Indonesia sebagai bunga dengan berbagai macam manfaat bagi kesehatan manusia salah satunya sebagai antibakteri, namun sayangnya belum diketahui seberapa jauh manfaat tersebut. Penelitian ini bertujuan untuk mengeksplorasi kandungan senyawa dan studi antibakteri ekstrak bunga telang menggunakan beberapa pelarut bersama dengan penilaian kritis terhadap potensinya di masa depan. Metode penelitian dilakukan dengan metode penelusuran literatur. Senyawa metabolit sekunder yang ditemukan pada ekstrak bunga telang seperti flavonoid, alkaloid, fenol, saponin dan tanin bertanggungjawab atas aktivitas antibakteri. Ekstrak bunga telang terbukti memberikan aktivitas antibakteri terhadap beberapa bakteri patogen penyebab konjungtivis, keracunan makanan, infeksi saluran kemih, infeksi kulit dan kerusakan gigi. Bakteri patogen seperti <em>P. aeruginosa, E. coli,</em> dan <em>S. aureus </em>berhasil<em> </em>dihambat pertumbuhannya<em> </em>dengan nilai Diameter Daya Hambat (DDH) 8 ‒ 26 mm. Aktivitas antibakteri yang dimilikinya dipengaruhi oleh pelarut yang digunakan, ekstrak metanol dengan konsentrasi 200 mg/mL memberikan aktivitas antibakteri yang paling kuat terhadap <em>P. aeruginosa</em> dengan nilai DDH 26 mm yang tergolong penghambatan kategori kuat. Hal ini membuktikan ekstrak bunga telang memiliki potensi untuk dikembangkan sebagai antibakteri alami.</p><p><strong>Antibacterial Activity of <em>Clitoria ternatea</em> L. Extract against Pathogenic Bacteria. </strong>Human disease can be caused by bacteria that cause infections. The use of plants as traditional has played an important role in health because it is considered as one of the most promising sources for the discovery of new antimicrobial agents with minimal side effects. Recently, <em>C. ternatea</em> has attracted much attention for Indonesian people as a flower with various benefits for human health, one of which is as an antibacterial. However, how far these benefits are still being investigated. For this reason, this study aims to explore the compound content and antibacterial studies of <em>C. ternatea</em> extract using several solvents along with a critical assessment of its potential in the future. The research method used was the literature search method. Secondary metabolite compounds found in <em>C. ternatea</em> extracts, such as flavonoids, alkaloids, phenols, saponins, and tannins, are responsible for the antibacterial activity. <em>C. ternatea</em> extract has antibacterial activity against several pathogenic bacteria that cause conjunctivitis, food poisoning, urinary tract infections, skin infections, and tooth decay. Pathogenic bacteria such as <em>P. aeruginosa</em>, <em>E. coli,</em> and <em>S. aureus</em> were inhibited with an inhibition zone value of 8 ‒ 26 mm. Its antibacterial activity is influenced by the solvent used, methanol extract with a concentration of 200 mg/mL gave the strongest activity against <em>P. aeruginosa</em> with an inhibition zone of 26 mm, classified as a strong inhibitory category. This proves that the <em>C. ternatea</em> extract has the potential to be further developed as a natural antibacterial agent.</p>

Pengembangan Metode Pembelajaran Berbasis Teaching Factory Pada Modul Praktikum Saponifikasi (Pembuatan Sabun Herbal)

“…Lengkuas merah (Alpinia purpurata) memiliki aktivitas antijamur, antioksidan, dan antibakteri (Sujono et al, 2019;Mardhiyyah et al, 2021;Hidayati et al, 2023); Ketepeng (Senna alata) diketahui juga memiliki aktivitas antijamur dan antibakteri (Legaspi & Maramba-Lazarte, 2020;Zakaria et al, 2022). Sementara itu, bunga telang telah diteliti memiliki aktivitas antibakteri dan antioksidan (Purwanto et al, 2022;Febrianti et al, 2022). Secara spesifik, ketiga bahan alam tersebut juga diketahui memiliki aktivitas antibakteri terhadap Escherichia coli (Yacob & Endriani, 2010;Fioni, 2021;Putri, Susilowati, & Mudyantini, 2022).…”

Studi Literatur Uji Aktivitas Antioksidan pada Ekstrak Bunga Telang (Clitoria ternatea L.) dengan Berbagai Metode Pengujian

“…yang semakin tinggi menunjukkan semakin rendah aktivitas antioksidan pada ekstrak bunga telang sedangkan nilai 𝐼𝐶 !" yang semakin rendah menunjukkan semakin tinggi aktivitas antioksidan [10]. Tabel 3.…”

Antibacterial and Antibiofilm Activities of Ternate Blue Pea (Clitoria ternatea) Flower Extract against Staphylococcus aureus

“…Pounded leaves of the telang flower are employed in treating festering wounds, while when boiled and combined with other plants, it proves beneficial in addressing vaginal discharge, as documented by Febrianti in 2022. 20 Febrianti et al (2022) observed that ternate Blue Pea plant extract (TBPE) is rich in secondary metabolites such as flavonoids, phenols, saponins, alkaloids, and tannins. These compounds confer antibacterial properties and offer additional benefits, including antifungal, antioxidant, anticancer, analgesic, and wound healing effects.…”

“…These compounds confer antibacterial properties and offer additional benefits, including antifungal, antioxidant, anticancer, analgesic, and wound healing effects. 20 The antibacterial potential of the Ternate Blue Pea plant prompts further exploration, particularly in the context of the native Ternate island in North Maluku plants, specifically as an antibacterial and antibiofilm agent. While research on the Ternate Blue Pea bioactivity is extensive, there remains a significant gap, particularly in its role as an antibacterial and antibiofilm agent against Staphylococcus aureus (SA), one of a causative agent of periodontal disease (PD).…”