Economic development is vital in each region, especially in improving regional problems. However, differences in total population, the minimum wage in the district/city, the human development index, the rate of open unemployment, and poverty can cause problems, one of which is income inequality. This study aims to analyze the effect of the number of residents, the minimum wage, the human development index, the level of open unemployment, and poverty on income inequality in 27 districts/cities in West Java from 2017 to 2021. The methodology used in this research is panel data (time series and cross-sectional) in 27 communities/cities in West Java for the 2017-2021 period. The model of choice used for this study is the fixed effect model (FEM). The results of this study show that population, wages, minimum district/city, and poverty are influential factors in income inequality. On the other hand, the human development index and the open unemployment rate have no significant impact on this survey.