This paper presents two methods, the block approach indefinite admittance matrix (BA-IAM) and the estimation-by-inspection, to analyse the effects of deterministic noise on single-stage, single-ended amplifiers by extending the indefinite admittance matrix. The proposed methods are used to develop a generalised two-port network analysis for the commonly used amplifier topologies, in the presence of the supply, ground, bulk, and input noise sources. Various illustrative case studies (common-source, common-gate, and push-pull amplifiers) are considered to validate the analytical method of different CMOS technology nodes (180 nm, 110 nm, and 28 nm) and foundries (Lfoundry, UMC, and TSMC). Both the proposed methods are compared with the relevant existing methods in terms of mean percentage error (MPE), and computational complexity. The mathematically derived expressions using two methods show less than 4% MPE when compared with the schematic simulation results, obtained by the SPICE based simulations. Also, the post-layout simulations (PLS) results for all the examples (designed in CMOS 180 nm Lfoundry technology) show excellent matching with schematic simulations. The proposed methods can be further applicable to antennas, complex circuits, digital circuits, etc.