Anti-<i>Schistosoma</i>IgG responses in<i>Schistosoma haematobium</i>single and concomitant infection with malaria parasites

Morenikeji, Olajumoke A.; Adeleye, Olumide; Omoruyi, Ewean Chukwuma; Oyeyemi, Oyetunde T.

doi:10.1080/20477724.2016.1174499

Cited by 4 publications

(1 citation statement)

References 29 publications

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“…Because it takes a long time for schistosomiasis chronic disease to manifest, its public health importance has been seriously downplayed. However, besides the great burden schistosomiasis could pose on the affected population, it is one of the NTDs that is closely associated with several other diseases like HIV/AIDS, malaria, bladder cancer, poliomyelitis, hepatitis, and urinary tract infections [ [56] , [57] , [58] , [59] , [60] , [61] , [62] ]. When S. haematobium finds its way into the female genitalia, it can cause primary and secondary infertility, and other disease sequelae which promote other infections like HIV and human papilloma virus (HPV).…”

Section: Prioritising Schistosomiasis Research In Neglected Groups Anmentioning

confidence: 99%

Schistosomiasis in Nigeria: Gleaning from the past to improve current efforts towards control

2020

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The effort to control schistosomiasis in Nigeria has been scaled up the past few years. Schistosomiasis affects all age groups, however, school children are at the highest risk of the disease. In the past years, global partners in schistosomiasis control have renewed their commitments. Many countries including few in Africa are working towards eliminating the disease. In Nigeria, the transmission of schistosomiasis is still active. This poses a serious health challenge as morbidity builds up in infected individuals. Mass drug administration (MDA) has helped to reduce morbidity but it is not adequate to abate transmission in many areas of the country. The integration of other aspects of control will provide a more sustainable result. This review attempted to discuss schistosomiasis transmission patterns in Nigeria in different eras. We identified some pitfalls in efforts towards the control of schistosomiasis in Nigeria. We recommended research priority in areas of neglect and advocated for integrated control.

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Section: Prioritising Schistosomiasis Research In Neglected Groups Anmentioning

confidence: 99%

Schistosomiasis in Nigeria: Gleaning from the past to improve current efforts towards control

2020

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Neglected tropical disease (NTD) diagnostics: current development and operations to advance control

Oyeyemi,

Ogundahunsi,

Schunk

et al. 2023

Pathogens and Global Health

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The extent, nature, and pathogenic consequences of helminth polyparasitism in humans: A meta-analysis

2019

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Background Individual helminth infections are ubiquitous in the tropics; geographical overlaps in endemicity and epidemiological reports suggest areas endemic for multiple helminthiases are also burdened with high prevalences of intestinal protozoan infections, malaria, tuberculosis (TB), and human immunodeficiency virus (HIV). Despite this, pathogens tend to be studied in isolation, and there remains a need for a better understanding of the community ecology and health consequences of helminth polyparasitism to inform the design of effective parasite control programs. Methodology We performed meta-analyses to (i) evaluate the commonality of polyparasitism for helminth-helminth, helminth-intestinal protozoa, helminth-malaria, helminth-TB, and helminth-HIV co-infections, (ii) assess the potential for interspecies interactions among helminth-helminth and helminth-intestinal protozoan infections, and (iii) determine the presence and magnitude of association between specific parasite pairs. Additionally, we conducted a review of reported health consequences of multiply-infected individuals compared to singly- or not multiply-infected individuals. Principal findings We found that helminth-helminth and helminth-intestinal protozoan multiple infections were significantly more common than single infections, while individuals with malaria, TB, and HIV were more likely to be singly-infected with these infections than co-infected with at least one helminth. Most observed species density distributions significantly differed from the expected distributions, suggesting the potential presence of interspecies interactions. All significant associations between parasite pairs were positive in direction, irrespective of the combination of pathogens. Polyparasitized individuals largely exhibited lower hemoglobin levels and higher anemia prevalence, while the differences in growth-related variables were mostly statistically insignificant. Conclusions Our findings confirm that helminth polyparasitism and co-infection with major diseases is common in the tropics. A multitude of factors acting at various hierarchical levels, such as interspecies interactions at the within-host infra-parasite community level and environmental variables at the higher host community level, could explain the observed positive associations between pathogens; there remains a need to develop new frameworks which can consider these multilevel factors to better understand the processes structuring parasite communities to accomplish their control.

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Anti-SchistosomaIgG responses inSchistosoma haematobiumsingle and concomitant infection with malaria parasites

Cited by 4 publications

References 29 publications

Schistosomiasis in Nigeria: Gleaning from the past to improve current efforts towards control

Schistosomiasis in Nigeria: Gleaning from the past to improve current efforts towards control

Neglected tropical disease (NTD) diagnostics: current development and operations to advance control

The extent, nature, and pathogenic consequences of helminth polyparasitism in humans: A meta-analysis

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