2017
DOI: 10.5530/pj.2018.1.14
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Anti-inflammatory Activity of Methanolic Extract from Pistacia atlantica Desf. Leaves

Abstract: Introduction:The extracts of the Pistacia species are known for their anti-inflammatory activity, including fruits and oil of P. atlantica. However, the inflammatory effect of the methanolic extract of P. atlantica leaves has not been studied. This work aimed at assessing the antiinflammatory and antioxidant activities of P. atlantica leaves extract in relation to phytochemical studies of flavonoids. Methods: The extract was obtained using sonication of leaves powder in 80 % methanol. The analysis of phenolic … Show more

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Cited by 41 publications
(29 citation statements)
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“…The results obtained can serve as a significant indicator for the antioxidant activity of the n-butanol extract which prompted us to subject it for further chromatographic isolation to identify its chemical constituents which may be responsible for such activity. Reviewing the literature revealed, several Chenopodium species were investigated for their in vitro antioxidant activities, i.e., Amri et al (2015) reported that the antioxidant activity of the 80% methanol extract of Moroccan Chenopodium ambrosioides equal to 73.80% 34 . In addition, the 80% MeOH of C. ambrosioides leaves growing in Egypt showed superoxide anion scavenging activity of 55.78% and iron chelating activity 73.37% 35 .…”
Section: In Vitro Antioxidant Activities (Dpph Tac)mentioning
confidence: 99%
“…The results obtained can serve as a significant indicator for the antioxidant activity of the n-butanol extract which prompted us to subject it for further chromatographic isolation to identify its chemical constituents which may be responsible for such activity. Reviewing the literature revealed, several Chenopodium species were investigated for their in vitro antioxidant activities, i.e., Amri et al (2015) reported that the antioxidant activity of the 80% methanol extract of Moroccan Chenopodium ambrosioides equal to 73.80% 34 . In addition, the 80% MeOH of C. ambrosioides leaves growing in Egypt showed superoxide anion scavenging activity of 55.78% and iron chelating activity 73.37% 35 .…”
Section: In Vitro Antioxidant Activities (Dpph Tac)mentioning
confidence: 99%
“…During inflammation, as part of their defensive roles, leukocytes release their lysosomal enzymes, including proteases, causing further tissue damage and subsequent inflammation [21]. The inflamed cells produce pro-inflammatory cytokines as well as stimulate the expression of nitric oxide synthase isoform, iNOS and COX [22]. Leukotrienes are derived from arachidonic acid via lipoxygenase pathway and are involved in the pathogenesis of several inflammatory diseases like asthma, psoriasis, rheumatoid arthritis, and inflammatory bowel diseases [23].…”
Section: Discussionmentioning
confidence: 99%
“…As the indomethacin caused the reduction in the weight gain by suppressing the in lammation, this mechanism was due to the inhibition of the prostaglandin synthesis in the site of in lammation that was induced by the cotton pellets [10,11]. When the extract lowered the in lammation in the same activity, it can be assumed that the extract also acted similarly and the mechanism was also assumed to be the same as compared to the indomethacin which is the inhibition of the synthesis of PG and cytokinin [12,13].…”
Section: Comparison Of Activitymentioning
confidence: 99%