Antibacterial activity and medicinal properties of ginger (&lt;i&gt;Zingiber officinale&lt;/i&gt;)

Malu, SP; Obochi, G.O.; Tawo, EN; Nyong, Bassey E.

doi:10.4314/gjpas.v15i3-4.48561

Cited by 75 publications

(67 citation statements)

References 5 publications

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“…The terpenoids are one of significant substances in pharmacy due to their connection with such compounds as vitamin A and have wide range of application in medicen. The gingerols could make ginger available for treatment of stomach acidity and may have analgesic and sedative properties (Malu et al 2009). …”

Section: Resultsmentioning

confidence: 99%

The role of spices and lactic acid bacteria as antimicrobial agent to extend the shelf life of metata ayib (traditional Ethiopian spiced fermented cottage cheese)

2015

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Spices and lactic acid bacteria have natural antimicrobial substances and organic compounds having antagonistic activity against microorganisms. The objective of this study was to investigate the role of spices and lactic acid bacteria as antimicrobial agent to extend the shelf life of metata ayib. Antimicrobial activities of spices and lactic acid bacteria (LAB) filtrates were determined by agar well diffusion method against E. coli, S. aureus, S. flexneri and S. peumoniae. Aantimicrobial activity of garlic was found to be the most effective against all the tested pathogens. Inhibition zones of garlic extract against all pathogens was significantly (P≤0.05) greater than the remaining spice extracts. Inhibition zones (12.50±1.00 to 15.50±1.00 mm) of ginger and R. graveolens ethanol extracts against all tested pathogens were significantly (P≤0.05) greater than the remaining solvent extracts. Inhibition zone of O. basilicum ethanol extract against all pathogenic bacteria was significantly (p≤0.05) greater than hexane and acetone extracts. Lactobacillus isolates were shown the highest antimicrobial activity than the other LAB isolates against all pathogens. The synergistic effect of spices together with LAB might be contributed a lot to preserve and extend shelf life of metata ayib. Their antimicrobial activity can reduce the risk of spoilage and pathogenesis. The possible reason of LAB isolates was may be due to production of lactic acid, acetic acid and secondary metabolites like bacteriocins. Aseptic processing of traditional cottage cheese (ayib) is by far needed to minimize risks associated during consumption of metata ayib.

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Section: Resultsmentioning

confidence: 99%

The role of spices and lactic acid bacteria as antimicrobial agent to extend the shelf life of metata ayib (traditional Ethiopian spiced fermented cottage cheese)

2015

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“…[1] Zingiberene is one of the major volatile oil present in the ginger extract along with sequesterpene, which causes the fragrance of the spice. [9] Successful prediction of bioactive compounds from plant material is largely dependent on the type of solvent used in the extraction procedure. In addition to the intrinsic bioactivity of the compound, the polarity of the compounds extracted from the solvent determines the ability to dissolve or diff use in the diff erent media used in the assay.…”

Section: Discussionmentioning

confidence: 99%

Inhibitory effects of ginger extract on Candida albicans, Staphylococcus aureus and Lactobacillus acidophilus

Murugesan¹,

Sivapathasundharam²

2016

IDJAR

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Background: The incidence of infections caused by yeast, particularly species of Candida and facultative anaerobic bacteria like Staphylococcus aureus and Lactobacillus acidophilus has increased dramatically during the past decade. Topical and systemic antifungal agents and anti microbial agents may be indicated to control oral candidiasis and periodontal and endodontic disease. The development of resistance is an emerging trend that may threaten the clinical eff ectiveness. Aim: An in vitro study to evaluate the antimicrobial effi cacy of ginger extract on Candida albicans, S. aureus, L. acidophilus, using fi ve diff erent polar organic solvents. Materials and Methods:The crude solvent extracts of ginger were prepared and subjected to antimicrobial assay using the Agar disk diff usion method to determine the zone of inhibition. The solvent extract with a signifi cant zone of inhibition is subjected to gas chromatography and mass spectrometry, to identify the bioactive constituent in the ginger extract. Result: Hexane extract of ginger shows high antimicrobial property, and the bioactive component was found to be zingiberene. Conclusion:The solvent extracts of ginger were proven to have eff ective antimicrobial property.

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“…They also reported that antimicrobial activity of the ethanol extract of ginger, lime and garlic against a broad range of bacteria including Bacillus spp., Staphylococcus aureus, Escherichia coli, and Salmonella spp. In another study, Malu et al [105] have carried out the antibacterial activity of ginger extracts. In their experiment, they obtained ginger extracts using solvents, n-hexane, ethyl acetate, ethanolic soxhlet and water.…”

Section: Antimicrobial Activitiesmentioning

confidence: 99%

Phychemistry, Phytochemical, Pharmacological and Molecular Study of Zingiber Officinale Roscoe: A Review

Ashraf

Sultan

Shah³

2017

Int J Pharm Pharm Sci

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The rhizomes of Zingiber officinale Roscoe (Zingiberaceae), commonly known as ginger, is one of the most widely used spice and condiment. It is also an integral part of many traditional medicines and has been extensively used in Chinese, Ayurvedic, Tibb-Unani, Srilankan, Arabic, and African traditional medicines, since antiquity, for many unrelated human ailments including common colds, fever, sore throats, vomiting, motion sickness, gastrointestinal complications, indigestion, constipation, gastritis, epigastric discomfort, gastric ulcerations, indigestion, nausea vomiting etc, and scientific studies have validated the ethnomedicinal uses. The present review tries to summarize and document the phytochemistry, phytochemical, pharmacological and molecular work done on ginger. The data was compiled to provide consolidated information covering different aspects of the plant, to provide a basis on which to plan future studies and to promote sustainable use of Z. officinale.

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Antibacterial activity and medicinal properties of ginger (<i>Zingiber officinale</i>)

Cited by 75 publications

References 5 publications

The role of spices and lactic acid bacteria as antimicrobial agent to extend the shelf life of metata ayib (traditional Ethiopian spiced fermented cottage cheese)

The role of spices and lactic acid bacteria as antimicrobial agent to extend the shelf life of metata ayib (traditional Ethiopian spiced fermented cottage cheese)

Inhibitory effects of ginger extract on Candida albicans, Staphylococcus aureus and Lactobacillus acidophilus

Phychemistry, Phytochemical, Pharmacological and Molecular Study of Zingiber Officinale Roscoe: A Review

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