Antibacterial activity of endophytic fungi extracts from the medicinal plant Kigelia africana.

Abstract

The aim of this study was to identify the endophytic fungi of the medicinal plant Kigelia africana (Lam) Benth. (Bignoniaceae) and to investigate their potential antimicrobial activity. Seven species of endophytic fungi were successfully isolated from K. Africana for the first time: including Cladosporium sp., Aspergillus flavus, Aspergillus sp., Curvularia lunata as well as three unknown species. The fungal extracts were assessed for antibacterial activity against three standard pathogenic bacterial strains: Bacillus subtilis, Staphylococcus aureus and Escherichia coli. Most of the extracts showed in vitro inhibition of bacterial growth. The phytochemical screening revealed the existence of a diverse group of secondary metabolites in the crude extracts of the endophytic fungi that resemble those in the host plant extracts.

Antifungal and antiproliferative activities of endophytic fungi isolated from the leaves of Markhamia tomentosa

“…It is well-established that protection of the plant host against pests and pathogens is in the best interest of both endophytes and the host genome itself (Idris et al. 2013 ). In this study, a dual culture assay ( Figure 2 ) was carried out to assess the antagonistic effects of the endophytic fungal strains isolated from M. tomentosa against four plant pathogenic fungi namely F. oxysporum (ITCC 3636), S. sclerotiorum (ITCC 6323), B. cinerea (ITCC 7478), and R. Solani (ITCC 6882).…”

Diversity of fungal endophyte of Ananus comosus L. var. kew from Unokoti district, Tripura with bioactive potential of Neopestalotiopsis piceana

“…The variation in inhibition zone diameter recorded in different experimental sets may be due to different bioactive compounds produced by endophytes or because of different concentration of the same compound (Mahapatra and Banerjee, 2010). Differences among the antimicrobial potency of the tested extract against bacterial strains might be due to either presence of unidentified active principle in the extracts in high concentration or probably in smaller amounts or the purification of the screened crude extracts could yield more potent compounds (Idris et al, 2013).…”

Evaluation of the Antimicrobial Effect of <i>Nepeta cataria</i> and <i>Basella alba</i> against Clinically Resistant <i>Acinetobacter baumannii</i> in Nairobi, Kenya

“…Using sterile swabs, the bacterial suspension of Acinetobacter baumannii was spread on the plates. Six millimeter well was cut in the plates with the sterile cork borer [19]. Using pipette, 100 µl of the solutions prepared was introduced into each well at different concentration.…”