Antibiotics in septoplasty: is it necessary?

Caniello, Marcello; Passerotti, Gustavo Haruo; Goto, Elder Yoshimitsu; Voegels, Richard Louis; Butugan, Ossamu

doi:10.1016/s1808-8694(15)31241-6

Cited by 38 publications

(47 citation statements)

References 10 publications

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“…Based on the best available evidence, current guidelines and review articles recommend the use of antimicrobial prophylaxis for the majority of cleancontaminated procedures. [6][7][8]497,520,521 However, antimicrobial prophylaxis did not lower infection risk in randomized controlled trials of patients undergoing adenoidectomy, tonsillectomy, 522,523 and septoplasty, 524 and systematic reviews have not recommended prophylaxis for these procedures. 7,525,526 The efficacy of antimicrobial prophylaxis is best established for head and neck cancer surgery.…”

Section: Head and Neck Proceduresmentioning

confidence: 99%

See 1 more Smart Citation

Clinical practice guidelines for antimicrobial prophylaxis in surgery

Bratzler

Dellinger

Olsen

et al. 2013

American Journal of Health-System Pharmacy

1,883

1,464

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Section: Head and Neck Proceduresmentioning

confidence: 99%

“…Studies of cleancontaminated head and neck procedures found no difference in efficacy between regimens of 24 hours and longer regimens of three, five, or seven days. [499][500][501]505,507,512,524,[531][532][533][534] Limited data exist on single-dose prophylaxis in these procedures.…”

Section: Head and Neck Proceduresmentioning

confidence: 99%

Clinical practice guidelines for antimicrobial prophylaxis in surgery

Bratzler

Dellinger

Olsen

et al. 2013

American Journal of Health-System Pharmacy

1,883

1,464

View full text Add to dashboard Cite

“…In the otolaryngologic field, transient bacteremia has been reported in many operation types, including septorhinoplasty, endoscopic sinus surgery, tonsillectomy, adenoidectomy, mastoidectomy, and tympanoplasty [26][27][28][29]. In the literature, only one study has demonstrated the relationship between bacteremia and the amount of bleeding; a significant correlation was observed during adenotonsillectomy [30].…”

Section: Discussionmentioning

confidence: 99%

The comparison of bacteremia and amount of bleeding during septoplasty

Koç

Uysal

et al. 2011

Eur Arch Otorhinolaryngol

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The aim of this study was to investigate the relationship between the amount of bleeding and bacteremia during nasal septal surgery. Seventy-one patients undergoing septoplasty were enrolled in the present study. The amount of bleeding was measured and recorded for each patient. Preoperative and postoperative blood cultures were collected immediately after the induction of anesthesia and 20 min after the operation, respectively. While none of the blood cultures taken preoperatively were positive for any organism, the cultures obtained postoperatively were positive in 9 (12.7%) of 71 patients who underwent septoplasty, and bacteremia was more frequent among those with a greater amount of bleeding during the surgery. The results of this study suggest that although bacteremia had no clinical consequences for patients, patients with more bleeding have an increased risk of developing bacteremia which may cause complications in higher risk individuals.

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“…8 Indiscriminate use of antibiotics can also cause toxic reactions. 9 Hence, judicious use of antibiotics is necessary.…”

Section: Aureusmentioning

confidence: 99%

Prophylactic use of antibiotics as per SIGN 104 guidelines versus routine antibiotic prophylaxis for prevention of surgical site infection in clean and clean contaminated ENT surgical procedures: a comparative study

Bharath

Galagali

Mishra

et al. 2019

Int J Otorhinolaryngol Head Neck Surg

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Background: Many clinicians continue to use antibiotic prophylaxis routinely in all surgical procedures, ignoring the guidelines issued by policy makers. In this prospective study we compared the rate of surgical site infection (SSI) in patients who received prophylactic antibiotics as a routine; with the rate of SSI in patients getting antibiotics strictly as per SIGN 104 Guidelines, for clean and clean contaminated procedures.Methods: The study population comprised 235 patients. Group A consisted of 119 patients having 77 (65%) males and 42 (35%) females while Group B had 116 patients - 71 (61%) males and 45 (39%) females. Group A received routine antibiotic prophylaxis in all cases, while Group B received antibiotic prophylaxis as per SIGN 104 guidelines only. Both the groups were followed up for one month post-operatively for SSI and complications.Results: SSI occurred in 2 patients (1.68%) in Group A and in 3 (2.59%) patients in Group B. There was no significant difference in the rate of SSI between the two groups (p=0.68). Procedure wise maximum SSI occurred in tympanoplasty and laryngectomy. Due to infection one case of tympanoplasty had graft failure and one case of laryngectomy had delayed wound healing. No major complications related to infection or antibiotic use occurred in either group.Conclusions: Selective use of antibiotic prophylaxis as per SIGN 104 Guidelines does not lead to increase in SSI in clean and clean contaminated ENT procedures.

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Antibiotics in septoplasty: is it necessary?

Abstract: The nasal surgeries are clean contamined and do not need antibioticprophilaxy because of the low infection risk.

Cited by 38 publications

References 10 publications

Clinical practice guidelines for antimicrobial prophylaxis in surgery

Clinical practice guidelines for antimicrobial prophylaxis in surgery

The comparison of bacteremia and amount of bleeding during septoplasty

Prophylactic use of antibiotics as per SIGN 104 guidelines versus routine antibiotic prophylaxis for prevention of surgical site infection in clean and clean contaminated ENT surgical procedures: a comparative study

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