Antimicrobial resistance in colonizing group B Streptococci before the implementation of a Swedish intrapartum antibiotic prophylaxis program

Survey of strain distribution and antibiotic resistance pattern of group B streptococci (Streptococcus agalactiae) isolated from clinical specimens

“…In Belgium, the prevalence of resistance to macrolide antibiotics among the invasive isolates increased from 10.4% in 2000 to 33% in 2008 [ 9 ]. These findings are in accordance with the reports from Europe [ 10 ], North America [ 11 ], and Asia [ 12 ], but some reports from Sweden explained these resistances lower than 10% [ 13 ]. The highest prevalence of resistance to erythromycin and clindamycin was reported by the study conducted by Dipersio et al; in that study 200 GBS isolates were collected from vaginal and rectal specimens, from them, 54% were resistant to erythromycin and 33% were resistant to clindamycin [ 1 ].…”

Prevalence of maternal group B streptococcus colonization and vertical transmission in low-risk women in a single institute

“…2,31 Therefore, intrapartum antibiotic prophylaxis could be an alternative, although concerns about allergy or resistance to antibiotics for GBS were present. 32 A recent study from France supported the current policy of GBS maternal prophylaxis, since it is not associated with an excessive risk of pathogen resistance. 33 Kaambwa et al tried to determine the cost-effectiveness of alternative screening and prevention strategies, including rapid intrapartum testing, for the prevention of early-onset neonatal GBS infection in the UK.…”

Nosocomial spread of multidrug-resistant group B streptococci with reduced penicillin susceptibility belonging to clonal complex 1

“…14 High rates of tetracycline resistance have also been noted among GBS isolates with the most common resistance determinant, tet(M), which encodes the ribosomal protection protein. 16,17 Our phylogenetic comparative analyses have shown genetic diversity of pbp genes among PRGBS strains, while those genes of the penicillin-susceptible strains were highly conserved, irrespective of their isolation dates. 2 Furthermore, a phylogenic tree showed three distinct genetic lineages of PRGBS strains, implying that those lineages have been independently emerging through the accumulation of different genetic mutations in their pbp genes during evolution.…”