Antimicrobial Screening and Phytochemical Analysis of Elaeis guineensis (Ewe Igi Ope) against Salmonella Strains

Ajayi, O. E.; Awala, Samuel Imisi; Ogunleye, A. G.; Okogbue, F. N.

doi:10.9734/bjpr/2016/23659

Cited by 7 publications

(3 citation statements)

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“…guineensis leaves and its tannin-free fraction contain alkaloids, flavonoids and terpenes. Phytochemical screening by other teams revealed the presence of these same major phytochemical groups in the methanolic extract of E. guineensis leaves (Sasidharan et al, 2010;Yin et al, 2013;Ajayi et al, 2016).…”

Section: Discussionmentioning

confidence: 98%

Anti-inflammatory and analgesic activities of methanolic extract of Elaeis guineensis Jacq. leaves (Arecaceae) and its fractions

Sene¹,

Firmin²,

Sarr³

et al. 2023

Afr. J. Pharm. Pharmacol.

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Elaeis guineensis Jacq. is an arborescent monocotyledon of the Arecaceae family. It is a plant originated from tropical rainforest of West Africa. For centuries, it has been a source of food and a natural remedy against several pathologies. The aim of the present research was to evaluate antiinflammatory and analgesic activities of methanolic extract E. guineensis Jacq. (Arecaceae) leaves and phytochemical groups. Extraction with methanol and various liquid-liquid fractionations were carried out. These extract and fractions were administered orally at different doses. The experiments were performed on models of carrageenan-induced inflammatory edema in rat and acetic acid-induced pain in mouse. The extraction protocols gave a methanolic extract and different fractions, methanolic tannins free, alkaloid, terpenoid, and flavonoid. The methanolic extract administered at doses of 1, 3 and 10 mg/kg significantly prevents inflammatory edema. The percentages of increase in edema 5 h after induction are 38.31±3.55, 37.48±4.98, 40.82±4.14 versus 92.72±6.05 in the control group. The same profiles are observed with the methanolic fractions tannins free, flavonoid and terpene. However, the latter show dose-dependent activities between 1 and 3 mg/kg. The methanol fraction tannins free at 3 mg/kg is better in preventing inflammatory edema. Oral tannin-free methanolic fraction significantly prevents acetic acid-induced pain in mice. Elaeis guineensis leaves possess anti-inflammatory and analgesic properties on models of carrageenan-induced inflammatory edema in rat and acetic acidinduced pain in mouse. The anti-inflammatory and analgesic activities could be linked to the combined action of alkaloids, flavonoids and terpenes, on the different targets of the inflammatory reaction.

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Section: Discussionmentioning

confidence: 98%

Anti-inflammatory and analgesic activities of methanolic extract of Elaeis guineensis Jacq. leaves (Arecaceae) and its fractions

Sene¹,

Firmin²,

Sarr³

et al. 2023

Afr. J. Pharm. Pharmacol.

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“…Aritonang et al (2021) also reported that its ethanolic extract effectively inhibited the growth of Propionibacterium acnes with a zone of inhibition of as much as 5.38 mm. The high contents of saponin, tannin, and flavonoid in the extract were considered active compounds responsible for this activity to coagulate bacterial protein and then impacted growth nutrition blockage in microorganisms ( Ajayi et al, 2016;Yin et al, 2013). Jaffri et al (2011) observed that the EGL extract showed antihypertensive and cardioprotective properties.…”

Section: Antioxidant Activitymentioning

confidence: 99%

Elaeis guineensis Jacq. leaves are a potential biomass for herbal medicine resources: A mini review

Sulistiarini¹,

Helmi²,

Narsa³

2022

j app pharm sci

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Indonesia, one of the first largest crude palm oil producer and exporter in the world, has a crucial problem with the reutilization of oil palm biomass. Elaeis guineensis Jacq. leaves (EGL) are the most abundant biomasses that are produced in the harvesting and producing process. However, the underutilization of this biomass still occurs in many industries and leads to environmental issues. This review aims to provide insight into the effort to discover and develop EGL as a potential biomass, especially for herbal medicine resources. We summarize several studies, focusing on the pharmacological activity of EGL and its bioactive chemical constituents. Results: We found 11 different pharmacological activities of the EGL extract, including antioxidant, antibacterial, antihypertensive, antidiabetic, immunomodulatory, diuretic, sun protection, wound healing, neuroprotective, gastroprotective, and antityrosinase activities, with flavonoid and phenolic acid as the highlighted compounds. The EGL extract showed various pharmacological actions, and it could be developed as a herbal medicine to treat several diseases.

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“…The mode of action of tannins is based majorly on their ability to bind proteins, thereby inhibiting cell protein synthesis [ 97 – 99 ]. The intervention of quorum sensing is in three levels: (i) signal synthesis, (ii) signal sequestration, and (iii) signal reception [ 100 ].…”

Section: Mechanisms Of Action Of Medicinal Plantsmentioning

confidence: 99%

Antimicrobial Importance of Medicinal Plants in Nigeria

Ugboko

Nwinyi

Oranusi

et al. 2020

The Scientific World Journal

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Despite the success of antibiotic discovery, infectious diseases remain the second leading source of death worldwide, while the resistance to antibiotics is among the significant problems in the twenty-first century. Medicinal plants are very rich in phytochemicals which can be structurally optimized and processed into new drugs. Nigeria enjoys a diverse collection of medicinal plants, and joint research has ascertained the efficacy of these plants. Plants such as guava (Psidium guajava), ginger (Zingiber officinale), neem (Azadirachta indica), and moringa (Moringa oleifera) have been found to exhibit broad range of antimicrobial activities. Studies on Nigerian plants have shown that they contain alkaloids, polyphenols, terpenes, glycosides, and others with possible therapeutic potentials. The antimicrobial activities of some new compounds such as alloeudesmenol, hanocokinoside, orosunol, and 8-demethylorosunol, identified from medicinal plants in Nigeria, are not yet explored. Further investigation and optimization of these compounds will facilitate the development of new sets of pharmacologically acceptable antimicrobial agents. This review study revealed the efficacy of medicinal plants as an alternative therapy in combating and curtailing the development and survival of multidrug-resistant pathogens coupled with the toxic effects of some antibiotics. Due to enormous therapeutic possibilities buried in medicinal plants, there is a need for more research into unique fingerprints and novel compounds that can provide cure to the neglected tropical diseases (NTDs) of humans and animals facing Africa, especially Nigeria.

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Antimicrobial Screening and Phytochemical Analysis of Elaeis guineensis (Ewe Igi Ope) against Salmonella Strains

Cited by 7 publications

References 0 publications

Anti-inflammatory and analgesic activities of methanolic extract of Elaeis guineensis Jacq. leaves (Arecaceae) and its fractions

Anti-inflammatory and analgesic activities of methanolic extract of Elaeis guineensis Jacq. leaves (Arecaceae) and its fractions

Elaeis guineensis Jacq. leaves are a potential biomass for herbal medicine resources: A mini review

Antimicrobial Importance of Medicinal Plants in Nigeria

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